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3D Printing Pharmaceuticals: Drug Development to Frontline Care

Trenfield, SJ; Awad, A; Goyanes, A; Gaisford, S; Basit, AW; (2018) 3D Printing Pharmaceuticals: Drug Development to Frontline Care. Trends in Pharmacological Sciences , 39 (5) pp. 440-451. 10.1016/j.tips.2018.02.006. Green open access

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Abstract

3D printing (3DP) is forecast to be a highly revolutionary technology within the pharmaceutical sector. In particular, the main benefits of 3DP lie in the production of small batches of medicines, each with tailored dosages, shapes, sizes and release characteristics. The manufacture of medicines in this way may finally lead to the concept of personalised medicines becoming a reality. In the shorter term, 3DP could be extended throughout the drug development process, ranging from preclinical development and clinical trials, through to frontline medical care. In this review, we provide a timely perspective on the motivations and potential applications of 3DP pharmaceuticals, as well as a practical viewpoint on how 3DP could be integrated across the pharmaceutical space.

Type: Article
Title: 3D Printing Pharmaceuticals: Drug Development to Frontline Care
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.tips.2018.02.006
Publisher version: https://doi.org/10.1016/j.tips.2018.02.006
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: additive manufacturing, clinical trials, drug development, first-in-human, personalised medicines, three-dimensional printing
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics
URI: https://discovery.ucl.ac.uk/id/eprint/10046863
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