McGranahan, N;
Swanton, C;
(2017)
Cancer Evolution Constrained by the Immune Microenvironment.
CELL
, 170
(5)
pp. 825-827.
10.1016/j.cell.2017.08.012.
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Abstract
Tumor development is a Darwinian evolutionary process, involving the interplay between cancer subclones and the local immune microenvironment. These complex interactions are highlighted in this issue of Cell by the results from Jiménez-Sánchez et al. of a deep analysis of one patient with advanced serous carcinoma of the ovary.
| Type: | Article |
|---|---|
| Title: | Cancer Evolution Constrained by the Immune Microenvironment |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.cell.2017.08.012 |
| Publisher version: | https://doi.org/10.1016/j.cell.2017.08.012 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, Cell Biology, CHECKPOINT BLOCKADE |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10046469 |
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