Zhang, A;
Jia, Y;
Almeida, P;
Mank, JE;
van Tuinen, M;
Wang, Q;
Jiang, Z;
... Qu, L; + view all
(2018)
Whole genome resequencing reveals signatures of selection and timing of duck domestication.
GigaScience
, 7
(4)
, Article giy027. 10.1093/gigascience/giy027.
Preview |
Text
Mank giy027.pdf Download (884kB) | Preview |
Abstract
Background The genetic basis of animal domestication remains poorly understood, and systems with substantial phenotypic differences between wild and domestic populations are useful for elucidating the genetic basis of adaptation to new environments as well as the genetic basis of rapid phenotypic change. Here, we sequenced the whole genome of 78 individual ducks, from two wild and seven domesticated populations, with an average sequencing depth of 6.42X per individual. Results Our population and demographic analyses indicate a complex history of domestication, with early selection for separate meat and egg lineages. Genomic comparison of wild to domesticated populations suggest that genes affecting brain and neuronal development have undergone strong positive selection during domestication. Our FST analysis also indicates that the duck white plumage is the result of selection at the melanogenesis associated transcription factor locus. Conclusions Our results advance the understanding of animal domestication and selection for complex phenotypic traits.
| Type: | Article |
|---|---|
| Title: | Whole genome resequencing reveals signatures of selection and timing of duck domestication |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1093/gigascience/giy027 |
| Publisher version: | https://doi.org/10.1093/gigascience/giy027 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10046384 |
Archive Staff Only
 |
View Item |
