Battiston, M;
Schneider, T;
Grussu, F;
Schenk, GJ;
Wergeland, S;
Tachrount, M;
Yiannakas, M;
... Samson, R; + view all
(2018)
Are we seeing any better? A comprehensive comparison of myelin biomarkers in the healthy and multiple sclerosis post mortem spinal cord.
In:
Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2018.
ISMRM: Paris, France.
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Abstract
Conventional MRI of the multiple sclerosis (MS) spinal cord offers low specificity to underlying pathological processes taking place. Quantitative MRI metrics able to characterize damage at the microstructural level are required. Of particular interest are those known to be sensitive to myelin content, which can be generated via various different contrast mechanisms. It is important to assess the specificity of such prospective myelin biomarkers to MS spinal cord pathology and validation studies comparing MRI with histological findings are essential for this purpose. Here a comparison of myelinsensitive quantitative MRI metrics measured in MS and healthy ex vivo cord are presented.
Type: | Proceedings paper |
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Title: | Are we seeing any better? A comprehensive comparison of myelin biomarkers in the healthy and multiple sclerosis post mortem spinal cord |
Event: | Joint Annual Meeting ISMRM-ESMRMB 2018 |
Location: | Paris |
Dates: | 15 June 2018 - 18 June 2018 |
Open access status: | An open access version is available from UCL Discovery |
Publisher version: | https://www.ismrm.org/18/program_files/O13.htm |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neuroinflammation |
URI: | https://discovery.ucl.ac.uk/id/eprint/10045177 |
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