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Integrating genomics to dig deeper into Wilms tumour biology

Mifsud, W; Pritchard-Jones, K; (2017) Integrating genomics to dig deeper into Wilms tumour biology. [Editorial comment]. Nature Reviews Urology , 14 (12) 10.1038/nrurol.2017.178. Green open access

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Abstract

A new study provides a comprehensive catalogue of the genetic changes in Wilms tumour. Understanding the interplay between genetic and epigenetic aberrations during tumorigenesis and clonal evolution is fundamental to enabling prediction of who is at risk and which tumours will relapse when so many are curable.

Type: Article
Title: Integrating genomics to dig deeper into Wilms tumour biology
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/nrurol.2017.178
Publisher version: http://doi.org/10.1038/nrurol.2017.178
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Cancer genomics, Epigenetics, Paediatric kidney disease, Wilms tumour
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10045114
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