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The pathological diagnosis of nerve biopsies: a practical approach

Brandner, S; (2016) The pathological diagnosis of nerve biopsies: a practical approach. Diagnostic Histopathology , 22 (9) pp. 333-344. 10.1016/j.mpdhp.2016.08.001. Green open access

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Abstract

The approach to the neuropathological assessment of nerve biopsies is the main focus of this review. Nerve biopsies are invasive diagnostic procedures resulting in a permanent neurological deficit, and are therefore carried out only following an in-depth clinical assessment including laboratory, imaging, electrophysiological, and where appropriate also genetic studies. This review will outline the key diagnostic approaches and will discuss neuropathies relevant in clinical practice, caused by vasculitis, inflammatory demyelination, dysproteinaemic, amyloid, toxic agents, and neuropathies due to genetic conditions.

Type: Article
Title: The pathological diagnosis of nerve biopsies: a practical approach
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.mpdhp.2016.08.001
Publisher version: http://dx.doi.org/10.1016/j.mpdhp.2016.08.001
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Amyloid neuropathyaxonal, demyelination, dysproteinaemic neuropathy, genetic neuropathy, inflammatory neuropathy, neuropathy, vasculitis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases
URI: https://discovery.ucl.ac.uk/id/eprint/10044514
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