UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Alcohol, pattern of drinking and all-cause mortality in Russia, Belarus and Hungary: a retrospective indirect cohort study based on mortality of relatives

Horvat, P; Stefler, D; Murphy, M; King, L; McKee, M; Bobak, M; (2018) Alcohol, pattern of drinking and all-cause mortality in Russia, Belarus and Hungary: a retrospective indirect cohort study based on mortality of relatives. Addiction , 113 (7) pp. 1252-1263. 10.1111/add.14189. Green open access

[thumbnail of Accepted manuscript]
Preview
Text (Accepted manuscript)
Horvat_Alcohol_pattern_drinking.pdf - Accepted Version

Download (880kB) | Preview
[thumbnail of Supplementary tables]
Preview
Text (Supplementary tables)
PrivMort - Supplement - Alcohol consumption and mortality in RU BE and HU 2nd revision.pdf - Accepted Version

Download (275kB) | Preview

Abstract

AIMS: To assess the relationship between alcohol intake frequency and mortality among males and females in three Eastern European populations, and to estimate the additional mortality risk posed by a combination of frequent drinking, binge drinking and other hazardous drinking habits. DESIGN: Retrospective cohort study; the cohort consisted of close relatives of survey participants. SETTING: Middle-sized settlements in Russia, Belarus and Hungary. PARTICIPANTS: 124,150 subjects aged 35-69 years in 1998 and followed-up until 2013. MEASUREMENTS: Survey respondents provided information on their mothers, fathers, siblings and partners of female respondents. This information, including current vital status and dates of birth and death, was used to construct the cohort of relatives. Alcohol consumption indices, reported by survey participants, included drinking frequency, binge drinking and hazardous drinking (consuming non-beverage and/or illicitly-produced alcohol and/or heavy drinking over several days [zapoi in Russian]). FINDINGS: Drinking frequency was positively associated with mortality in all three countries and both genders. At each drinking frequency level, mortality risk increased among those who also engaged in binge and/or hazardous drinking. Regular male drinkers who were also binge drinkers and hazardous drinkers had the highest risk of death; their hazard ratios (HR), compared with non-binge-non-hazardous occasional drinkers, were 2.56 [95% CI 2.27-2.88], 2.14 [1.84-2.48] and 2.11 [1.90-2.35] in Russia, Belarus and Hungary, respectively. In women, the corresponding HRs (using a lower frequency cut-off) were 2.86 [1.99-4.12] in Russia, 3.44 [2.17-5.44] in Belarus and 3.01 [2.26-4.01] in Hungary. CONCLUSIONS: Drinking frequency is positively associated with mortality among men and women in Russia, Belarus and Hungary. The mortality risk is higher among frequent drinkers who exhibit binge and hazardous drinking patterns.

Type: Article
Title: Alcohol, pattern of drinking and all-cause mortality in Russia, Belarus and Hungary: a retrospective indirect cohort study based on mortality of relatives
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/add.14189
Publisher version: http://dx.doi.org/10.1111/add.14189
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/10043866
Downloads since deposit
329Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item