Sanders, RD;
Winston, JS;
Barnes, GR;
Rees, G;
(2018)
Magnetoencephalographic Correlates of Perceptual State During Auditory Bistability.
Scientific Reports
, 8
, Article 976. 10.1038/s41598-018-19287-0.
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Abstract
Bistability occurs when two alternative percepts can be derived from the same physical stimulus. To identify the neural correlates of specifc subjective experiences we used a bistable auditory stimulus and determined whether the two perceptual states could be distinguished electrophysiologically. Fourteen participants underwent magnetoencephalography while reporting their perceptual experience while listening to a continuous bistable stream of auditory tones. Participants reported bistability with a similar overall proportion of the two alternative percepts (52% vs 48%). At the individual level, sensor space electrophysiological discrimination between the percepts was possible in 9/14 participants with canonical variate analysis (CVA) or linear support vector machine (SVM) analysis over space and time dimensions. Classifcation was possible in 14/14 subjects with non-linear SVM. Similar efects were noted in an unconstrained source space CVA analysis (classifying 10/14 participants), linear SVM (classifying 9/14 subjects) and non-linear SVM (classifying 13/14 participants). Source space analysis restricted to a priori ROIs showed discrimination was possible in the right and left auditory cortex with each classifcation approach but in the right intraparietal sulcus this was only apparent with non-linear SVM and only in a minority of particpants. Magnetoencephalography can be used to objectively classify auditory experiences from individual subjects.
| Type: | Article |
|---|---|
| Title: | Magnetoencephalographic Correlates of Perceptual State During Auditory Bistability |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/s41598-018-19287-0 |
| Publisher version: | http://dx.doi.org/10.1038/s41598-018-19287-0 |
| Language: | English |
| Additional information: | Open Access: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Te images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. © The Author(s) 2018. |
| Keywords: | Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, BINOCULAR-RIVALRY, STREAM SEGREGATION, CONSCIOUS EXPERIENCE, BISTABLE PERCEPTION, TONE SEQUENCES, ORGANIZATION, CORTEX, RESPONSES, LEAD |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10042452 |
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