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Nanoparticle–membrane interactions

Contini, C; Schneemilch, M; Gaisford, S; Quirke, N; (2017) Nanoparticle–membrane interactions. Journal of Experimental Nanoscience , 13 (1) pp. 62-81. 10.1080/17458080.2017.1413253. Green open access

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Abstract

Engineered nanomaterials have a wide range of applications and as a result, are increasingly present in the environment. While they offer new technological opportunities, there is also the potential for adverse impact, in particular through possible toxicity. In this review, we discuss the current state of the art in the experimental characterisation of nanoparticle-membrane interactions relevant to the prediction of toxicity arising from disruption of biological systems. One key point of discussion is the urgent need for more quantitative studies of nano-bio interactions in experimental models of lipid system that mimic in vivo membranes.

Type: Article
Title: Nanoparticle–membrane interactions
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/17458080.2017.1413253
Publisher version: http://doi.org/10.1080/17458080.2017.1413253
Language: English
Additional information: © 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/ licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Nanotoxicity, nanomaterial, membrane interface, nanoparticle
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics
URI: https://discovery.ucl.ac.uk/id/eprint/10041318
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