Valente, V;
Demosthenous, A;
(2017)
A 32-by-32 CMOS microelectrode array for capacitive biosensing and impedance spectroscopy.
In:
Circuits and Systems (ISCAS), 2017 IEEE International Symposium on.
IEEE: Baltimore, MD, USA.
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Abstract
This paper presents the design of a 1024-channel dual-modality CMOS biosensor suitable for both capacitive sensing and impedance spectroscopy. The chip serves as a platform for detection, localization and monitoring of bacteria and can be adopted for affinity-based assays. The chip features a 32×32 array of unpassivated metal electrodes formed on the top metal of a 0.18μm CMOS process, with an overall sensing area of 2.06 mm2. The system design is based on a shared in-pixel integrator that can be used as a charge amplifier for capacitive sensing (CS) or as part of a transimpedance amplifier for electrical impedance spectroscopy (EIS). The CS mode is capable of a operation bandwidth of 50 MHz at a current consumption of 82 μA per pixel. The EIS channel operates over a bandwidth between 100 Hz and 1 MHz with a total input-referred current noise of 48 pArms and a current consumption of 210 μA per channel.
Type: | Proceedings paper |
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Title: | A 32-by-32 CMOS microelectrode array for capacitive biosensing and impedance spectroscopy |
Event: | 2017 IEEE International Symposium on Circuits and Systems (ISCAS) |
ISBN-13: | 9781467368520 |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1109/ISCAS.2017.8050734 |
Publisher version: | https://doi.org/10.1109/ISCAS.2017.8050734 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
Keywords: | Impedance, Capacitors, Spectroscopy, Bandwidth, Sensor arrays, Gain |
UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Electronic and Electrical Eng |
URI: | https://discovery.ucl.ac.uk/id/eprint/10039265 |
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