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Inter-observer agreement among uveitis experts on uveitic diagnoses: the Standardization of Uveitis Nomenclature (SUN) experience

Jabs, DA; Dick, A; Doucette, JT; Gupta, A; Lightman, S; McCluskey, P; Okada, AA; ... Standardization of Uveitis Nomenclature (SUN) Working Group; + view all (2017) Inter-observer agreement among uveitis experts on uveitic diagnoses: the Standardization of Uveitis Nomenclature (SUN) experience. American Journal of Ophthalmology 10.1016/j.ajo.2017.10.028. (In press). Green open access

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Abstract

PURPOSE: To evaluate the interobserver agreement among uveitis experts on the diagnosis of the specific uveitic disease. DESIGN: Inter-observer agreement analysis METHODS: Five committees, each of 9 individuals, working in parallel, reviewed cases from a preliminary database of 25 uveitic diseases, collected by disease, and voted independently online whether the case was the disease in question or not. The agreement statistic, κ, was calculated for the 36 pairwise comparisons for each disease, and a mean κ was calculated for each disease. Following the independent online voting, committee consensus conference calls, using nominal group techniques, reviewed all cases not achieving supermajority agreement (>75%) on the diagnosis in the online voting to attempt to arrive at a supermajority agreement. RESULTS: A total of 5766 cases for the 25 diseases were evaluated. The overall mean κ for the entire project was 0.39 with disease-specific variation from 0.23 to 0.79. After the formalized consensus conference calls to address cases which did not achieve supermajority agreement in the online voting, supermajority agreement overall was reached on ∼99% of cases with disease-specific variation from 96 to 100%. CONCLUSIONS: Agreement among uveitis experts on diagnosis is moderate at best but can be improved by discussion among them. These data suggest the need for validated and widely-used classification criteria in the field of uveitis.

Type: Article
Title: Inter-observer agreement among uveitis experts on uveitic diagnoses: the Standardization of Uveitis Nomenclature (SUN) experience
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ajo.2017.10.028
Publisher version: http://dx.doi.org/10.1016/j.ajo.2017.10.028
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Diagnosis, Inter-observer agreement, Uveitis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10038891
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