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Pulmonary rehabilitation and cardiovascular risk in COPD: a systematic review

Aldabayan, YS; Alrajeh, AM; Lemson, A; Hurst, JR; (2017) Pulmonary rehabilitation and cardiovascular risk in COPD: a systematic review. COPD Research and Practice , 3 (1) 10.1186/s40749-017-0026-9. Green open access

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Abstract

Introduction: Pulmonary Rehabilitation (PR) is an effective intervention in COPD however the value of PR in reducing cardiovascular risk in COPD (measured by aortic pulse wave velocity, aPWV) is unclear and there is no existing systematic review. Objectives: To conduct a systematic review examining whether PR results in alteration of CV risk in COPD (as measured by aPWV). Methods: An electronic systematic search concordant with PRISMA guidelines was conducted. The search was complete to the 27th of May 2017. Six databases were examined: Embase, Medline, AMED, Web of Science, Cochrane clinical trials, and CINAHL. Results: This study generated 767 initial matches, which were filtered using inclusion/exclusion criteria. Three studies (201 COPD participants) were included. Our analysis does not confirm that PR affects aPWV but studies were heterogeneous. Conclusion: There is currently insufficient information on the effect of PR on reducing CV risk in COPD. Therefore controversy remains, with the possibility that there might be some subjects who benefit and others who might experience an increase in CV risk in response to PR. These results will be of value to those interested in gaining a better understanding of the benefits of PR on CV risk in COPD.

Type: Article
Title: Pulmonary rehabilitation and cardiovascular risk in COPD: a systematic review
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/s40749-017-0026-9
Publisher version: http://dx.doi.org/10.1186/s40749-017-0026-9
Language: English
Additional information: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Pulmonary rehabilitation, Cardiovascular, COPD, Arterial stiffness
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10038094
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