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Dynapenic abdominal obesity increases mortality risk among English and Brazilian older adults: A 10-year follow-up of the ELSA and SABE studies

Da Silva Alexandre, T; Scholes, S; Ferreira Santos, JL; De Oliveira Duarte, YA; De Oliveira, C; (2018) Dynapenic abdominal obesity increases mortality risk among English and Brazilian older adults: A 10-year follow-up of the ELSA and SABE studies. Journal of Nutrition, Health and Aging , 22 (1) pp. 138-144. 10.1007/s12603-017-0966-4. Green open access

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Abstract

BACKGROUND/OBJECTIVE: There is little epidemiological evidence demonstrating that dynapenic abdominal obesity has higher mortality risk than dynapenia and abdominal obesity alone. Our main aim was to investigate whether dynapenia combined with abdominal obesity increases mortality risk among English and Brazilian older adults over ten-year follow-up. DESIGN: Cohort study. SETTING: United Kingdom and Brazil. PARTICIPANTS: Data came from 4,683 individuals from the English Longitudinal Study of Ageing (ELSA) and 1,490 from the Brazilian Health, Well-being and Aging study (SABE), hence the final sample of this study was 6,173 older adults. MEASUREMENTS: The study population was categorized into the following groups: nondynapenic/ non-abdominal obese, abdominal obese, dynapenic, and dynapenic abdominal obese according to their handgrip strength (< 26 kg for men and < 16 kg for women) and waist circumference (> 102 cm for men and > 88 cm for women). The outcome was all-cause mortality over a ten-year follow-up. Adjusted hazard ratios by sociodemographic, behavioural and clinical characteristics were estimated using Cox proportional hazards models. Results: The fully adjusted model showed that dynapenic abdominal obesity has a higher mortality risk among the groups. The hazard ratios (HR) were 1.37 for dynapenic abdominal obesity (95% CI = 1.12–1.68), 1.15 for abdominal obesity (95% CI = 0.98–1.35), and 1.23 for dynapenia (95% CI = 1.04–1.45). CONCLUSIONS: Dynapenia is an important risk factor for mortality but dynapenic abdominal obesity has the highest mortality risk among English and Brazilian older adults.

Type: Article
Title: Dynapenic abdominal obesity increases mortality risk among English and Brazilian older adults: A 10-year follow-up of the ELSA and SABE studies
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s12603-017-0966-4
Publisher version: https://doi.org/10.1007/s12603-017-0966-4
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Dynapenia, handgrip waist, circumference, obesity, mortality
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/10035820
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