Shallcross, L;
Gaskell, K;
Fox-Lewis, A;
Bergstrom, M;
Noursadeghi, M;
(2018)
Mismatch between suspected pyelonephritis and microbiological diagnosis: a cohort study from a UK teaching hospital.
Journal of Hospital Infection
, 98
(2)
pp. 219-222.
10.1016/j.jhin.2017.09.029.
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Abstract
Urinary tract infections are a common reason for prescribing empirical antibiotics in the emergency department. This study investigated the role of microbiological culture and urinalysis in the diagnosis of pyelonephritis by extracting data on 105 patients with a clinical diagnosis of pyelonephritis at a London teaching hospital. In total, 99 of 102 patients were treated empirically with intravenous antibiotics, but only 55 of 100 patients who were sampled had microbiological evidence of infection in urine and/or blood. Almost half (10/21) of the patients with a negative urine dipstick test had a positive urine culture. Diagnostic uncertainty in this context undoubtedly drives inappropriate antibiotic use.
| Type: | Article |
|---|---|
| Title: | Mismatch between suspected pyelonephritis and microbiological diagnosis: a cohort study from a UK teaching hospital |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.jhin.2017.09.029 |
| Publisher version: | http://doi.org/10.1016/j.jhin.2017.09.029 |
| Language: | English |
| Additional information: | © 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved. This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Antibiotic stewardship, Antimicrobial resistance, Diagnostics, Urinary tract infection |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10029830 |
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