UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

An overview of concepts and approaches used in estimating the burden of congenital disorders globally

Moorthie, S; Blencowe, H; Darlison, MW; Lawn, JE; Mastroiacovo, P; Morris, JK; Modell, B; (2018) An overview of concepts and approaches used in estimating the burden of congenital disorders globally. Journal of Community Genetics , 9 (4) pp. 347-362. 10.1007/s12687-017-0335-3. Green open access

[img]
Preview
Text
Darlison_An overview of concepts and approaches used in estimating the burden of congenital disorders globally_VoR.pdf

Download (1MB) | Preview

Abstract

Congenital disorders are an important cause of pregnancy loss, premature death and life-long disability. A range of interventions can greatly reduce their burden, but the absence of local epidemiological data on their prevalence and the impact of interventions impede policy and service development in many countries. In an attempt to overcome these deficiencies, we have developed a tool—The Modell Global Database of Congenital Disorders (MGDb) that combines general biological principles and available observational data with demographic data, to generate estimates of the birth prevalence and effects of interventions on mortality and disability due to congenital disorders. MGDb aims to support policy development by generating country, regional and global epidemiological estimates. Here we provide an overview of the concepts and methodological approach used to develop MGDb.

Type: Article
Title: An overview of concepts and approaches used in estimating the burden of congenital disorders globally
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s12687-017-0335-3
Publisher version: http://dx.doi.org/10.1007/s12687-017-0335-3
Language: English
Additional information: © The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/).
Keywords: Congenital disorders, Epidemiology, Policy, Public Health
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Primary Care and Population Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics > CHIME
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health > Maternal and Fetal Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10027476
Downloads since deposit
59Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item