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Diagnosis of Latent Tuberculosis Infection in HIV-infected Pregnant Women. “Baby Steps” toward Better Tuberculosis Control in Pregnancy

Zenner, D; Ashkin, D; (2016) Diagnosis of Latent Tuberculosis Infection in HIV-infected Pregnant Women. “Baby Steps” toward Better Tuberculosis Control in Pregnancy. [Editorial comment]. American Journal of Respiratory and Critical Care Medicine , 193 (12) pp. 1332-1333. 10.1164/rccm.201601-0156ED. Green open access

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Abstract

Despite significant reductions in incidence, the global burden of tuberculosis (TB) is immense. In 2014, there were an estimated 9.6 million new cases, accounting for 1.1 million deaths, with an estimated 1.2 million (12.5%) of these new cases being in patients infected with HIV. Although TB is more common among men, globally TB is a leading cause of death among women of childbearing age. The higher risk for TB during pregnancy, as well as adverse outcomes for mother and child, have been previously recognized (2–5) and are potentially related to the physiological partial inhibition of the cellular immune system necessary to tolerate the fetus.

Type: Article
Title: Diagnosis of Latent Tuberculosis Infection in HIV-infected Pregnant Women. “Baby Steps” toward Better Tuberculosis Control in Pregnancy
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1164/rccm.201601-0156ED
Publisher version: https://doi.org/10.1164/rccm.201601-0156ED
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Tuberculosis (TB), HIV, Pregnancy, Cellular immune system
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/10027066
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