Baird, Gillian; Charman, Tony; Pickles, Andrew; Chandler, Susie; Loucas, Tom; Meldrum, David; Carcani-Rathwell, I; ... Simonoff, Emily; + view all Baird, Gillian; Charman, Tony; Pickles, Andrew; Chandler, Susie; Loucas, Tom; Meldrum, David; Carcani-Rathwell, I; Serkana, I; Simonoff, Emily; - view fewer (2008) Regression, developmental trajectory and associated problems in disorders in the autism spectrum: the SNAP study. Journal of Autism and Developmental Disorders , 38 pp. 1827-1836.

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Abstract

We report rates of regression and associated findings in a population derived group of 255 children aged 9-14 years, participating in a prevalence study of autism spectrum disorders (ASD); 53 with narrowly defined autism, 105 with broader ASD and 97 with non-ASD neurodevelopmental problems, drawn from those with special educational needs within a population of 56,946 children. Language regression was reported in 30% with narrowly defined autism, 8% with broader ASD and less than 3% with developmental problems without ASD. A smaller group of children were identified who underwent a less clear setback. Regression was associated with higher rates of autistic symptoms and a deviation in developmental trajectory. Regression was not associated with epilepsy or gastrointestinal problems.

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