eprintid: 73893
rev_number: 70
eprint_status: archive
userid: 608
dir: disk0/00/07/38/93
datestamp: 2010-10-17 10:03:49
lastmod: 2021-10-09 22:31:31
status_changed: 2014-01-08 11:18:57
type: proceedings_section
metadata_visibility: show
item_issues_count: 0
creators_name: Patel, S
creators_name: Katura, T
creators_name: Maki, A
creators_name: Tachtsidis, I
title: Quantification of Systemic Interference in Optical Topography Data during Frontal Lobe and Motor Cortex Activation: An Independent Component Analysis
ispublished: pub
divisions: UCL
divisions: B04
divisions: C05
divisions: F42
keywords: Near-infrared spectroscopy, functional activation
note: © 2011 Springer Verlag. The original publication is available at www.springerlink.com
abstract: Functional near-infrared optical topography (OT) is used to non-invasively measure the changes in oxygenated and deoxygenated haemoglobin (Delta[HbO(2)], Delta[HHb]) and hence investigate the brain haemodynamic changes, which occur in response to functional activation at specific regions of the cerebral cortex. However, when analysing functional OT data the task-related systemic changes should be taken into account. Here we used an independent component analysis (ICA) method on the OT [HbO(2)] signal, to determine the task-related independent components and then compared them with the systemic measurements (blood pressure, heart rate, scalp blood flow) to assess whether the components are due to systemic noise or neuronal activation. This analysis can therefore extract the true OT haemodynamic neuronal response and hence discriminate between regional activated cortical areas and global haemodynamic changes.
date: 2011
publisher: Springer Verlag
official_url: http://dx.doi.org/10.1007/978-1-4419-7756-4_7
vfaculties: VENG
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
article_type_text: Proceedings Paper
verified: verified_manual
elements_source: Web of Science
elements_id: 125493
doi: 10.1007/978-1-4419-7756-4_7
isbn_13: 9781441977557
lyricists_name: Tachtsidis, Ilias
lyricists_id: ITACH19
full_text_status: public
series: Advances in Experimental Medicine and Biology
publication: OXYGEN TRANSPORT TO TISSUE XXXII
volume: 701
place_of_pub: Berlin/ Heidelberg, Germany
pagerange: 45 - 51
event_title: 37th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT)
event_location: Cleveland, OH, US
event_dates: 5 - 9 July, 2009
issn: 0065-2598
book_title: Oxygen Transport to Tissue XXXII
editors_name: LaManna, JC
editors_name: Puchowicz, MA
editors_name: Xu, K
editors_name: Harrison, DK
editors_name: Bruley, DF
citation:        Patel, S;    Katura, T;    Maki, A;    Tachtsidis, I;      (2011)    Quantification of Systemic Interference in Optical Topography Data during Frontal Lobe and Motor Cortex Activation: An Independent Component Analysis.                     In: LaManna, JC and Puchowicz, MA and Xu, K and Harrison, DK and Bruley, DF, (eds.) Oxygen Transport to Tissue XXXII.  (pp. 45 - 51).  Springer Verlag: Berlin/ Heidelberg, Germany.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/73893/1/Patel_et_al_AdvExpMedBiol_2011.pdf