TY  - JOUR
SP  - 76 
Y1  - 2007///
AV  - public
ID  - discovery2897
SN  - 0969-1413
JF  - J MED SCREEN
UR  - http://ukpmc.ac.uk/abstract/MED/17626706
N2  - Objective To assess uptake of once-only flexible sigmoidoscopy (FS) in a community sample to determine whether FS would be viable as a method of population-based screening for colorectal cancer.Methods All adults aged 60-64 years registered at three General Practices in North West London, UK (5 10 men and women) were sent a letter of invitation to attend FS screening carried out by an experienced nurse, followed by a reminder if they did not make contact to confirm or decline the invitation. The primary outcome was attendance at the endoscopy unit for a FS test.Results Of the 510 people invited to attend, 280 (55%) underwent FS. Among non-attenders, 91 (18%) were ineligible for screening or did not receive the invitation, 19 (4%) accepted the offer of screening but were unable to attend during the study period, 52 (10%) declined the offer, 41 (8%) did not respond to the invitation, and 27 (5%) accepted the offer of screening but did not attend. Attendance among those eligible to be screened, who had received the invitation, was 67%. People from more socioeconomically deprived neighbourhoods were less likely to attend (odds ratio [OR] = 0.90; confidence interval [0] = 0.84-0.96; P = 0.003). Women were more likely to attend than men (OR = 1.44; CI = 1.01-2.05; P = 0.041).Conclusions Attendance rates in this pilot for nurse-led, population-based FS screening were higher than those reported in other FS studies, and comparable with adherence to fecal occult blood testing (FOBT) in the UK FOBT pilot. Having a female nurse endoscopist may have been responsible for increasing female uptake rates but this warrants confirmation in a larger study.
KW  - FECAL OCCULT BLOOD
KW  -  MULTICENTER RANDOMIZED TRIAL
KW  -  ONCE-ONLY SIGMOIDOSCOPY
KW  -  SURVIVAL DIFFERENCES
KW  -  UNITED-KINGDOM
KW  -  LINE FINDINGS
KW  -  MORTALITY
KW  -  ENDOSCOPISTS
KW  -  PREVENTION
KW  -  DIAGNOSIS
PB  - ROYAL SOC MEDICINE PRESS LTD
VL  - 14
IS  - 2
A1  - Brotherstone, H
A1  - Vance, M
A1  - Edwards, R
A1  - Miles, A
A1  - Robb, KA
A1  - Evans, REC
A1  - Wardle, J
A1  - Atkin, W
TI  - Uptake of population-based flexible sigmoidoscopy screening for colorectal cancer: a nurse-led feasibility study
EP  -  80
ER  -