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<https://discovery.ucl.ac.uk/id/eprint/2491> <http://purl.org/dc/terms/title> "Improved effectiveness of partner notification for patients\r\nwith sexually transmitted infections: systematic review"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/2491> <http://purl.org/ontology/bibo/abstract> "Objective: To examine the effectiveness of methods to\r\nimprove partner notification by patient referral (index\r\npatient has responsibility for informing sex partners of\r\ntheir exposure to a sexually transmitted infection).\r\nDesign: Systematic review of randomised trials of any\r\nintervention to supplement simple patient referral.\r\nData sources: Seven electronic databases searched\r\n(January 1990 to December 2005) without language\r\nrestriction, and reference lists of retrieved articles.\r\nReview methods: Selection of trials, data extraction, and\r\nquality assessment were done by two independent\r\nreviewers. The primary outcome was a reduction of\r\nincidence or prevalence of sexually transmitted\r\ninfections in index patients. If this was not reported data\r\nwere extracted according to a hierarchy of secondary\r\noutcomes: number of partners treated; number of\r\npartners tested or testing positive; and number of\r\npartners notified, located, or elicited. Random effects\r\nmeta-analysis was carried out when appropriate.\r\nResults: 14 trials were included with 12 389 women and\r\nmen diagnosed as having gonorrhoea, chlamydia, nongonococcal\r\nurethritis, trichomoniasis, or a sexually\r\ntransmitted infection syndrome. All studies had\r\nmethodological weaknesses that could have biased\r\ntheir results. Three strategies were used. Six trials\r\nexamined patient delivered partner therapy. Metaanalysis\r\nof five of these showed a reduced risk of\r\npersistent or recurrent infection in patients with\r\nchlamydia or gonorrhoea (summary risk ratio 0.73, 95%\r\nconfidence interval 0.57 to 0.93). Supplementing\r\npatient referral with information for partners was as\r\neffective as patient delivered partner therapy. Neither\r\nstrategy was effective in women with trichomoniasis.\r\nTwo trials found that providing index patients with\r\nchlamydia with sampling kits for their partners\r\nincreased the number of partners who got treated.\r\nConclusions: Involving index patients in shared\r\nresponsibility for the management of sexual partners\r\nimproves outcomes. Health professionals should\r\nconsider the following strategies for the management of\r\nindividual patients: patient delivered partner therapy,\r\nhome sampling for partners, and providing additional\r\ninformation for partners."^^<http://www.w3.org/2001/XMLSchema#string> .
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