TY  - JOUR
SP  - 641
VL  - 31
N1  - This version is the author accepted manuscript. For information on re-use, please refer to the publisher?s terms and conditions.
IS  - 6
SN  - 1461-7285
UR  - http://doi.org/10.1177/0269881116689260
JF  - Journal of Psychopharmacology
A1  - Stanford, SC
TI  - Confusing preclinical (predictive) drug screens with animal "models' of psychiatric disorders, or "disorder-like' behaviour, is undermining confidence in behavioural neuroscience
EP  - 643
AV  - public
Y1  - 2017/06/01/
ID  - discovery1559744
N2  - Preclinical (predictive) screens for psychotropic drugs are often used, incorrectly, as animal ?models? of psychiatric disorders, or to study ?disorder-like?
behaviours. This misunderstanding is contributing to poor translation and is undermining confidence in behavioural neuroscience. In this editorial, I
discuss some of the reasons why the interpretation of results from many of these procedures is dubious because the criteria for validity of the test, as
a model of the disorder, have been ignored. Arising from this, I propose that the description of any abnormal behaviour of rodents as a ?model? of a
psychiatric disorder, or even ?disorder-like?, without evidence-based justification, should be regarded as unacceptable in this journal.
PB  - SAGE PUBLICATIONS LTD
ER  -