eprintid: 1559692 rev_number: 30 eprint_status: archive userid: 608 dir: disk0/01/55/96/92 datestamp: 2017-06-18 00:08:19 lastmod: 2021-10-03 23:46:23 status_changed: 2017-06-20 10:04:17 type: article metadata_visibility: show creators_name: Lawson, RP creators_name: Aylward, J creators_name: Roiser, JP creators_name: Rees, G title: Adaptation of social and non-social cues to direction in adults with autism spectrum disorder and neurotypical adults with autistic traits ispublished: inpress divisions: UCL divisions: B02 divisions: C07 divisions: D05 divisions: F69 divisions: C08 keywords: Adaptation, Autism, Autistic traits, Directional cues, Sensory processing, Social cues note: Copyright © 2017 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/BY/4.0/). abstract: Perceptual constancy strongly relies on adaptive gain control mechanisms, which shift perception as a function of recent sensory history. Here we examined the extent to which individual differences in magnitude of adaptation aftereffects for social and non-social directional cues are related to autistic traits and sensory sensitivity in healthy participants (Experiment 1); and also whether adaptation for social and non-social directional cues is differentially impacted in adults with Autism Spectrum Disorder (ASD) relative to neurotypical (NT) controls (Experiment 2). In Experiment 1, individuals with lower susceptibility to adaptation aftereffects, i.e. more 'veridical' perception, showed higher levels of autistic traits across social and non-social stimuli. Furthermore, adaptation aftereffects were predictive of sensory sensitivity. In Experiment 2, only adaptation to eye-gaze was diminished in adults with ASD, and this was related to difficulties categorizing eye-gaze direction at baseline. Autism Diagnostic Observation Schedule (ADOS) scores negatively predicted lower adaptation for social (head and eye-gaze direction) but not non-social (chair) stimuli. These results suggest that the relationship between adaptation and the broad socio-cognitive processing style captured by 'autistic traits' may be relatively domain-general, but in adults with ASD diminished adaptation is only apparent where processing is most severely impacted, such as the perception of social attention cues. date: 2017-05-17 date_type: published official_url: http://doi.org/10.1016/j.dcn.2017.05.001 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1298427 doi: 10.1016/j.dcn.2017.05.001 pii: S1878-9293(16)30168-2 lyricists_name: Lawson, Rebecca lyricists_name: Rees, Geraint lyricists_name: Roiser, Jonathan lyricists_id: RLAWS68 lyricists_id: GEREE91 lyricists_id: JPROI43 actors_name: Waragoda Vitharana, Nimal actors_id: NWARR44 actors_role: owner full_text_status: public publication: Developmental Cognitive Neuroscience event_location: Netherlands issn: 1878-9307 citation: Lawson, RP; Aylward, J; Roiser, JP; Rees, G; (2017) Adaptation of social and non-social cues to direction in adults with autism spectrum disorder and neurotypical adults with autistic traits. Developmental Cognitive Neuroscience 10.1016/j.dcn.2017.05.001 <https://doi.org/10.1016/j.dcn.2017.05.001>. (In press). Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/1559692/1/Lawson_%2B1-s2.0-S1878929316301682-main.pdf