eprintid: 1555801
rev_number: 23
eprint_status: archive
userid: 608
dir: disk0/01/55/58/01
datestamp: 2017-05-13 19:55:29
lastmod: 2021-10-06 22:35:09
status_changed: 2017-06-12 10:00:46
type: article
metadata_visibility: show
creators_name: Kendrick, D
creators_name: Kelllezi, B
creators_name: Coupland, C
creators_name: Maula, A
creators_name: Beckett, K
creators_name: Morriss, R
creators_name: Joseph, S
creators_name: Barnes, J
creators_name: Sleney, J
creators_name: Christie, N
title: Psychological morbidity and health-related quality of life after injury: multicentre cohort study
ispublished: pub
divisions: UCL
divisions: B04
divisions: C05
divisions: F44
keywords: Unintentional injury; Quality of life; Depression; Anxiety; Cohort study
note: Copyright © The Author(s) 2016. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
abstract: PURPOSE: To demonstrate the impact of psychological morbidity 1 month post-injury on subsequent post-injury quality of life (HRQoL) in a general injury population in the UK to inform development of trauma care and rehabilitation services.

METHODS: Multicentre cohort study of 16–70-year-olds admitted to 4 UK hospitals following injury. Psychological morbidity and HRQoL (EQ-5D-3L) were measured at recruitment and 1, 2, 4 and 12 months post-injury. A reduction in EQ-5D compared to retrospectively assessed pre-injury levels of at least 0.074 was taken as the minimal important difference (MID). Multilevel logistic regression explored relationships between psychological morbidity 1 month post-injury and MID in HRQoL over the 12 months after injury.

RESULTS: A total of 668 adults participated. Follow-up rates were 77% (1 month) and 63% (12 months). Substantial reductions in HRQoL were seen; 93% reported a MID at 1 month and 58% at 12 months. Problems with pain, mobility and usual activities were commonly reported at each time point. Depression and anxiety scores 1 month post-injury were independently associated with subsequent MID in HRQoL. The relationship between depression and HRQoL was partly explained by anxiety and to a lesser extent by pain and social functioning. The relationship between anxiety and HRQoL was not explained by factors measured in our study.

CONCLUSIONS: Hospitalised injuries result in substantial reductions in HRQoL up to 12 months later. Depression and anxiety early in the recovery period are independently associated with lower HRQoL. Identifying and managing these problems, ensuring adequate pain control and facilitating social functioning are key elements in improving HRQoL post-injury.
date: 2017-05
date_type: published
publisher: SPRINGER
official_url: http://dx.doi.org/10.1007/s11136-016-1439-7
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
article_type_text: Article
verified: verified_manual
elements_id: 1189908
doi: 10.1007/s11136-016-1439-7
lyricists_name: Christie, Nicola
lyricists_id: NCHRI60
full_text_status: public
publication: Quality of Life Research
volume: 26
number: 5
pagerange: 1233-1250
pages: 18
issn: 1573-2649
citation:        Kendrick, D;    Kelllezi, B;    Coupland, C;    Maula, A;    Beckett, K;    Morriss, R;    Joseph, S;             ... Christie, N; + view all <#>        Kendrick, D;  Kelllezi, B;  Coupland, C;  Maula, A;  Beckett, K;  Morriss, R;  Joseph, S;  Barnes, J;  Sleney, J;  Christie, N;   - view fewer <#>    (2017)    Psychological morbidity and health-related quality of life after injury: multicentre cohort study.                   Quality of Life Research , 26  (5)   pp. 1233-1250.    10.1007/s11136-016-1439-7 <https://doi.org/10.1007/s11136-016-1439-7>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1555801/1/Kendrick_Psychological_morbidity_health-related_quality_of_life.pdf
document_url: https://discovery.ucl.ac.uk/id/eprint/1555801/2/Kendrick_Psychological_morbidity_health-related_quality_of_life_Tables.pdf
document_url: https://discovery.ucl.ac.uk/id/eprint/1555801/3/Kendrick_Psychological_morbidity_health-related_quality_of_life_Figures.pdf