eprintid: 1544876
rev_number: 27
eprint_status: archive
userid: 608
dir: disk0/01/54/48/76
datestamp: 2017-03-12 00:46:26
lastmod: 2021-10-07 22:04:02
status_changed: 2017-05-08 09:56:58
type: article
metadata_visibility: show
creators_name: Heller, MK
creators_name: Chapman, SCE
creators_name: Horne, R
title: No blank slates: Pre-existing schemas about pharmaceuticals predict memory for side effects
ispublished: pub
divisions: UCL
divisions: B02
divisions: C08
divisions: D10
divisions: G11
keywords: Science & Technology, Social Sciences, Life Sciences & Biomedicine, Public, Environmental & Occupational Health, Psychology, Multidisciplinary, Psychology, Pharmaceutical Schemas, Memory, Side Effects, Beliefs About Medicines, Questionnaire, Perceived Sensitivity To Medicines Scale, Fuzzy-Trace Theory, Rheumatoid-Arthritis, Medical Information, Attentional Biases, Medicines, Beliefs, Adherence, Illness, Representation, Sensitivity
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: OBJECTIVES: Attribution of symptoms as medication side effects is informed by pre-existing beliefs about medicines and perceptions of personal sensitivity to their effects (pharmaceutical schemas). We tested whether (1) pharmaceutical schemas were associated with memory (recall/recognition) for side effect information (2) memory explained the attribution of a common unrelated symptom as a side effect.


DESIGN: In this analogue study participants saw the patient leaflet of a fictitious asthma drug listing eight side effects.

MAIN OUTCOME MEASURES: We measured recall and recognition memory for side effects and used a vignette to test whether participants attributed an unlisted common symptom (headache) as a side effect.

RESULTS: Participants who perceived pharmaceuticals as more harmful in general recalled fewer side effects correctly (rCorrect Recall = −.273), were less able to differentiate between listed and unlisted side effects (rRecognition Sensitivity = −.256) and were more likely to attribute the unlisted headache symptom as a side effect (rside effect attribution = .381, ps < .01). The effect of harm beliefs on side effect attribution was partially mediated by correct recall of side effects.

CONCLUSION: Pharmaceutical schemas are associated with memory for side effect information. Memory may explain part of the association between pharmaceutical schemas and the attribution of unrelated symptoms as side effects.
date: 2017-01
date_type: published
publisher: TAYLOR & FRANCIS LTD
official_url: http://dx.doi.org/10.1080/08870446.2016.1273355
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
article_type_text: Article
verified: verified_manual
elements_id: 1210598
doi: 10.1080/08870446.2016.1273355
language_elements: eng
lyricists_name: Horne, Robert
lyricists_id: RHORN95
full_text_status: public
publication: Psychology and Health
volume: 32
number: 4
pagerange: 402-421
pages: 20
issn: 1476-8321
citation:        Heller, MK;    Chapman, SCE;    Horne, R;      (2017)    No blank slates: Pre-existing schemas about pharmaceuticals predict memory for side effects.                   Psychology and Health , 32  (4)   pp. 402-421.    10.1080/08870446.2016.1273355 <https://doi.org/10.1080/08870446.2016.1273355>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1544876/1/Home_No%20blank%20states%20revision.pdf