eprintid: 1542415
rev_number: 57
eprint_status: archive
userid: 608
dir: disk0/01/54/24/15
datestamp: 2017-02-23 17:06:52
lastmod: 2021-10-04 01:55:15
status_changed: 2017-10-12 09:10:06
type: article
metadata_visibility: show
creators_name: Hagen, CK
creators_name: Diemoz, PC
creators_name: Olivo, A
title: On the relative performance of edge illumination x-ray phase contrast CT and conventional, attenuation-based CT
ispublished: pub
divisions: UCL
divisions: B04
divisions: C05
divisions: F42
abstract: Purpose

This article is aimed at comparing edge illumination (EI) x-ray phase contrast computed tomography (PCT) and conventional (attenuation-based) computed tomography (CT), based on their respective contrast and noise transfer.
Methods

The noise in raw projections obtained with EI PCT is propagated through every step of the data processing, including phase retrieval and tomographic reconstruction, leading to a description of the noise in the reconstructed phase tomograms. This is compared to the noise in corresponding attenuation tomograms obtained with CT. Specifically, a formula is derived that allows evaluating the relative performance of both modalities on the basis of their contrast-to-noise ratio (CNR), for a variety of experimental parameters.
Results

The noise power spectra of phase tomograms are shifted towards lower spatial frequencies, leading to a fundamentally different noise texture. The relative performance of EI PCT and CT, in terms of their CNR, is linked to spatial resolution: the CNR in phase tomograms is generally superior to that in attenuation tomograms for higher spatial resolutions (tens to hundreds of μm), but inferior for lower spatial resolutions (hundreds of μm to mm).
Conclusions

These results imply that EI PCT could outperform CT in applications for which high spatial resolutions are key, i.e. small animal or specimen imaging.

This article is protected by copyright. All rights reserved.
date: 2017-02-25
date_type: published
publisher: American Association of Physicists in Medicine
official_url: http://dx.doi.org/10.1002/mp.12179
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
article_type_text: Article
verified: verified_manual
elements_id: 1209996
doi: 10.1002/mp.12179
lyricists_name: Diemoz, Paul
lyricists_name: Hagen, Charlotte
lyricists_name: Olivo, Alessandro
lyricists_id: PCDIE01
lyricists_id: CKHAG69
lyricists_id: AOLIV86
actors_name: Bracey, Alan
actors_id: ABBRA90
actors_role: owner
full_text_status: public
publication: Medical Physics
volume: 44
number: 5
pagerange: 1876-1885
issn: 0094-2405
citation:        Hagen, CK;    Diemoz, PC;    Olivo, A;      (2017)    On the relative performance of edge illumination x-ray phase contrast CT and conventional, attenuation-based CT.                   Medical Physics , 44  (5)   pp. 1876-1885.    10.1002/mp.12179 <https://doi.org/10.1002/mp.12179>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1542415/1/Hagen_et_al-2017-Medical_Physics.2-10.pdf