@article{discovery1542264, pages = {827--833}, note = {{\copyright} 2016 American Chemical Society. ACS AuthorChoice - This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.}, volume = {17}, journal = {Crystal Growth and Design}, title = {Are oxygen and sulfur atoms structurally equivalent in organic crystals?}, year = {2017}, number = {2}, month = {February}, url = {http://doi.org/10.1021/acs.cgd.6b01669}, abstract = {New guidelines for the design of structurally equivalent molecular crystals were derived from structural analyses of new cocrystals and polymorphs of saccharin and thiosaccharin, aided by a computational study. The study shows that isostructural crystals may be obtained through an exchange of {\ensuremath{>}}C?O with {\ensuremath{>}}C?S in the molecular components of the solids, but only if the exchanged atom is not involved in hydrogen bonding.}, issn = {1528-7505}, author = {Corpinot, MK and Guo, R and Tocher, DA and Buanz, ABM and Gaisford, S and Price, SL and Bu{\vc}ar, DK} }