<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> . <> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/1540293> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/title> "Chlamydia trachomatis Pgp3 Antibody Population Seroprevalence before and during an Era of Widespread Opportunistic Chlamydia Screening in England (1994-2012)"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/abstract> "BACKGROUND: Opportunistic chlamydia screening of <25 year-olds was nationally-implemented in England in 2008 but its impact on chlamydia transmission is poorly understood. We undertook a population-based seroprevalence study to explore the impact of screening on cumulative incidence of chlamydia, as measured by C.trachomatis-specific antibody. METHODS: Anonymised sera from participants in the nationally-representative Health Surveys for England (HSE) were tested for C.trachomatis antibodies using two novel Pgp3 enzyme-linked immunosorbent assays (ELISAs) as a marker of past infection. Determinants of being seropositive were explored using logistic regression among 16-44 year-old women and men in 2010 and 2012 (years when sexual behaviour questions were included in the survey) (n = 1,402 women; 1,119 men). Seroprevalence trends among 16-24 year-old women (n = 3,361) were investigated over ten time points from 1994-2012. RESULTS: In HSE2010/2012, Pgp3 seroprevalence among 16-44 year-olds was 24.4% (95%CI 22.0-27.1) in women and 13.9% (11.8-16.2) in men. Seroprevalence increased with age (up to 33.5% [27.5-40.2] in 30-34 year-old women, 18.7% [13.4-25.6] in 35-39 year-old men); years since first sex; number of lifetime sexual partners; and younger age at first sex. 76.7% of seropositive 16-24 year-olds had never been diagnosed with chlamydia. Among 16-24 year-old women, a non-significant decline in seroprevalence was observed from 2008-2012 (prevalence ratio per year: 0.94 [0.84-1.05]). CONCLUSION: Our application of Pgp3 ELISAs demonstrates a high lifetime risk of chlamydia infection among women and a large proportion of undiagnosed infections. A decrease in age-specific cumulative incidence following national implementation of opportunistic chlamydia screening has not yet been demonstrated. We propose these assays be used to assess impact of chlamydia control programmes."^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/date> "2017-01-27" . <https://discovery.ucl.ac.uk/id/document/340025> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery.ucl.ac.uk/id/document/342024> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery.ucl.ac.uk/id/document/342025> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery.ucl.ac.uk/id/document/342026> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery.ucl.ac.uk/id/document/342027> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/volume> "12" . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/issue> "1" . <https://discovery.ucl.ac.uk/id/publication/ext-19326203> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> . <https://discovery.ucl.ac.uk/id/publication/ext-19326203> <http://xmlns.com/foaf/0.1/name> "PLoS One"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-19326203> . <https://discovery.ucl.ac.uk/id/publication/ext-19326203> <http://www.w3.org/2002/07/owl#sameAs> <urn:issn:19326203> . <https://discovery.ucl.ac.uk/id/publication/ext-19326203> <http://purl.org/ontology/bibo/issn> "19326203" . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> . <https://discovery.ucl.ac.uk/id/eprint/1540293> 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<http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-85dbc984aadd548d05adacc9702f68c1> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> . <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-85dbc984aadd548d05adacc9702f68c1> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b9a854d8c638c57abad4d20ce8415dba> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> . <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-b9a854d8c638c57abad4d20ce8415dba> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-8bae49f750db3e7883a9f92b2445bc45> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> . <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-8bae49f750db3e7883a9f92b2445bc45> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f02f2ccb7be9436d3519c9f6f9303219> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> . <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-f02f2ccb7be9436d3519c9f6f9303219> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-3d3401e340d15ab52b07f6e43427332a> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> . <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-3d3401e340d15ab52b07f6e43427332a> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-95a9293666420d5c86bb1f6a7d82df0c> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> . <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-95a9293666420d5c86bb1f6a7d82df0c> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-e7024749610379a3f4b9acfa11549392> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> . <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-e7024749610379a3f4b9acfa11549392> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-91057586628ad5f555e867c68e9cb511> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> . <https://discovery.ucl.ac.uk/id/eprint/1540293#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-91057586628ad5f555e867c68e9cb511> . <https://discovery.ucl.ac.uk/id/person/ext-370a428bb1b355fc634f3020212c8a57> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-370a428bb1b355fc634f3020212c8a57> <http://xmlns.com/foaf/0.1/givenName> "GS"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-370a428bb1b355fc634f3020212c8a57> <http://xmlns.com/foaf/0.1/familyName> "Wills"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-370a428bb1b355fc634f3020212c8a57> <http://xmlns.com/foaf/0.1/name> "GS Wills"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b9a854d8c638c57abad4d20ce8415dba> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-b9a854d8c638c57abad4d20ce8415dba> <http://xmlns.com/foaf/0.1/givenName> "R"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b9a854d8c638c57abad4d20ce8415dba> <http://xmlns.com/foaf/0.1/familyName> "Craig"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b9a854d8c638c57abad4d20ce8415dba> <http://xmlns.com/foaf/0.1/name> "R Craig"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-3d3401e340d15ab52b07f6e43427332a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-3d3401e340d15ab52b07f6e43427332a> <http://xmlns.com/foaf/0.1/givenName> "MO"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-3d3401e340d15ab52b07f6e43427332a> <http://xmlns.com/foaf/0.1/familyName> "McClure"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-3d3401e340d15ab52b07f6e43427332a> <http://xmlns.com/foaf/0.1/name> "MO McClure"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-f02f2ccb7be9436d3519c9f6f9303219> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-f02f2ccb7be9436d3519c9f6f9303219> <http://xmlns.com/foaf/0.1/givenName> "G"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-f02f2ccb7be9436d3519c9f6f9303219> <http://xmlns.com/foaf/0.1/familyName> "Murphy"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-f02f2ccb7be9436d3519c9f6f9303219> <http://xmlns.com/foaf/0.1/name> "G Murphy"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-95a9293666420d5c86bb1f6a7d82df0c> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-95a9293666420d5c86bb1f6a7d82df0c> <http://xmlns.com/foaf/0.1/givenName> "K"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-95a9293666420d5c86bb1f6a7d82df0c> <http://xmlns.com/foaf/0.1/familyName> "Soldan"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-95a9293666420d5c86bb1f6a7d82df0c> <http://xmlns.com/foaf/0.1/name> "K Soldan"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e7024749610379a3f4b9acfa11549392> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-e7024749610379a3f4b9acfa11549392> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e7024749610379a3f4b9acfa11549392> <http://xmlns.com/foaf/0.1/familyName> "Nardone"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e7024749610379a3f4b9acfa11549392> <http://xmlns.com/foaf/0.1/name> "A Nardone"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-8bae49f750db3e7883a9f92b2445bc45> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-8bae49f750db3e7883a9f92b2445bc45> <http://xmlns.com/foaf/0.1/givenName> "JS"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-8bae49f750db3e7883a9f92b2445bc45> <http://xmlns.com/foaf/0.1/familyName> "Mindell"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-8bae49f750db3e7883a9f92b2445bc45> <http://xmlns.com/foaf/0.1/name> "JS Mindell"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b43a3fba9521ffbfdb3782441c323ed5> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-b43a3fba9521ffbfdb3782441c323ed5> <http://xmlns.com/foaf/0.1/givenName> "SC"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b43a3fba9521ffbfdb3782441c323ed5> <http://xmlns.com/foaf/0.1/familyName> "Woodhall"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b43a3fba9521ffbfdb3782441c323ed5> <http://xmlns.com/foaf/0.1/name> "SC Woodhall"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-91057586628ad5f555e867c68e9cb511> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-91057586628ad5f555e867c68e9cb511> <http://xmlns.com/foaf/0.1/givenName> "AM"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-91057586628ad5f555e867c68e9cb511> <http://xmlns.com/foaf/0.1/familyName> "Johnson"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-91057586628ad5f555e867c68e9cb511> <http://xmlns.com/foaf/0.1/name> "AM Johnson"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-85dbc984aadd548d05adacc9702f68c1> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-85dbc984aadd548d05adacc9702f68c1> <http://xmlns.com/foaf/0.1/givenName> "PJ"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-85dbc984aadd548d05adacc9702f68c1> <http://xmlns.com/foaf/0.1/familyName> "Horner"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-85dbc984aadd548d05adacc9702f68c1> <http://xmlns.com/foaf/0.1/name> "PJ Horner"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/EPrint> . <https://discovery.ucl.ac.uk/id/eprint/1540293> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/ArticleEPrint> . 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