@article{discovery1529542,
            note = {{\copyright} 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)},
           month = {January},
          volume = {86},
         journal = {Cortex},
           pages = {33--44},
           title = {Hippocampal and diencephalic pathology in developmental amnesia.},
            year = {2017},
        keywords = {Hippocampus, Hypoxia-ischaemia, Mammillary bodies, Memory, Thalamus},
             url = {http://dx.doi.org/10.1016/j.cortex.2016.09.016},
            issn = {1973-8102},
        abstract = {Developmental amnesia (DA) is a selective episodic memory disorder associated with hypoxia-induced bilateral hippocampal atrophy of early onset. Despite the systemic impact of hypoxia-ischaemia, the resulting brain damage was previously reported to be largely limited to the hippocampus. However, the thalamus and the mammillary bodies are parts of the hippocampal-diencephalic network and are therefore also at risk of injury following hypoxic-ischaemic events. Here, we report a neuroimaging investigation of diencephalic damage in a group of 18 patients with DA (age range 11-35 years), and an equal number of controls. Importantly, we uncovered a marked degree of atrophy in the mammillary bodies in two thirds of our patients. In addition, as a group, patients had mildly reduced thalamic volumes. The size of the anterior-mid thalamic (AMT) segment was correlated with patients' visual memory performance. Thus, in addition to the hippocampus, the diencephalic structures also appear to play a role in the patients' memory deficit.},
          author = {Dzieciol, AM and Bachevalier, J and Saleem, KS and Gadian, DG and Saunders, R and Chong, WK and Banks, T and Mishkin, M and Vargha-Khadem, F}
}