eprintid: 1516215
rev_number: 29
eprint_status: archive
userid: 608
dir: disk0/01/51/62/15
datestamp: 2016-11-04 13:48:14
lastmod: 2020-02-13 07:02:06
status_changed: 2016-11-04 13:48:14
type: article
metadata_visibility: show
creators_name: Morgan, MY
title: Current state of knowledge of hepatic encephalopathy (part III): non-absorbable disaccharides
ispublished: pub
divisions: UCL
divisions: A01
divisions: B02
divisions: C10
divisions: D17
divisions: G91
keywords: Hepatic encephalopathy, efficacy, lactitol, lactulose, safety
note: © The Author(s) 2016. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
abstract: Nonabsorbable disaccharides have been the mainstay of treatment for hepatic encephalopathy since introduced into clinical practice in 1966. Their beneficial effects reflect their ability to reduce the intestinal production/absorption of ammonia. A recent Cochrane review confirmed the efficacy and safety of nonabsorbable disaccharides for the treatment and prevention of hepatic encephalopathy in patients with cirrhosis. The findings were robust and support the use of nonabsorbable disaccharides as a first line treatment for hepatic encephalopathy, in this patient population, and for its prevention.
date: 2016-09-16
date_type: published
official_url: http://doi.org/10.1007/s11011-016-9910-2
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
article_type_text: Journal Article
verified: verified_manual
elements_id: 1160252
doi: 10.1007/s11011-016-9910-2
pii: 10.1007/s11011-016-9910-2
lyricists_name: Morgan, Marsha
lyricists_id: MYMOR45
actors_name: Morgan, Marsha
actors_id: MYMOR45
actors_role: owner
full_text_status: public
publication: Metabolic Brain Disease
volume: 31
number: 6
pagerange: 1361-1364
event_location: United States
issn: 1573-7365
citation:        Morgan, MY;      (2016)    Current state of knowledge of hepatic encephalopathy (part III): non-absorbable disaccharides.                   Metabolic Brain Disease , 31  (6)   pp. 1361-1364.    10.1007/s11011-016-9910-2 <https://doi.org/10.1007/s11011-016-9910-2>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1516215/1/art%253A10.1007%252Fs11011-016-9910-2.pdf