eprintid: 1514941
rev_number: 27
eprint_status: archive
userid: 608
dir: disk0/01/51/49/41
datestamp: 2016-09-11 03:17:18
lastmod: 2021-09-29 22:40:42
status_changed: 2016-11-09 12:05:09
type: article
metadata_visibility: show
creators_name: Bartlett, RD
creators_name: Choi, D
creators_name: Phillips, JB
title: Biomechanical properties of the spinal cord: implications for tissue engineering and clinical translation
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D07
divisions: F82
divisions: C08
divisions: D10
divisions: G10
keywords: Science & Technology, Life Sciences & Biomedicine, Technology, Cell & Tissue Engineering, Engineering, Biomedical, Cell Biology, Engineering, biomechanical properties, biomechanics, CNS, mechanical properties, regenerative medicine, spinal cord, spinal cord injury, spinal cord repair, tissue engineering, MAGNETIC-RESONANCE ELASTOGRAPHY, CENTRAL-NERVOUS-SYSTEM, TRAUMATIC BRAIN-INJURY, MECHANICAL-PROPERTIES, WHITE-MATTER, VISCOELASTIC PROPERTIES, IN-VIVO, BIOLOGICAL TISSUES, FORCE MICROSCOPY, MR ELASTOGRAPHY
note: This is the peer reviewed version of the following article: James B. Phillips, Biomechanical properties of the spinal cord: implications for tissue engineering and clinical translation, Regenerative Medicine
October 2016 ,Vol. 11, No. 7, Pages 659-673, which has been published in final form at: 10.2217/rme-2016-0065
abstract: Spinal cord injury is a severely debilitating condition which can leave individuals paralyzed and suffering from autonomic dysfunction. Regenerative medicine may offer a promising solution to this problem. Previous research has focused primarily on exploring the cellular and biological aspects of the spinal cord, yet relatively little remains known about the biomechanical properties of spinal cord tissue. Given that a number of regenerative strategies aim to deliver cells and materials in the form of tissue-engineered therapies, understanding the biomechanical properties of host spinal cord tissue is important. We review the relevant biomechanical properties of spinal cord tissue and provide the baseline knowledge required to apply these important physical concepts to spinal cord tissue engineering.
date: 2016-10-01
date_type: published
publisher: FUTURE MEDICINE LTD
official_url: http://dx.doi.org/10.2217/rme-2016-0065
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
article_type_text: Review
verified: verified_manual
elements_id: 1157704
doi: 10.2217/rme-2016-0065
language_elements: English
lyricists_name: Choi, David
lyricists_name: Phillips, James
lyricists_id: DCHOI64
lyricists_id: JBPHI82
actors_name: Phillips, James
actors_name: Barczynska, Patrycja
actors_id: JBPHI82
actors_id: PBARC91
actors_role: owner
actors_role: impersonator
full_text_status: public
publication: Regenrative Medicine
volume: 11
number: 7
pagerange: 659-673
pages: 15
issn: 1746-0751
citation:        Bartlett, RD;    Choi, D;    Phillips, JB;      (2016)    Biomechanical properties of the spinal cord: implications for tissue engineering and clinical translation.                   Regenrative Medicine , 11  (7)   pp. 659-673.    10.2217/rme-2016-0065 <https://doi.org/10.2217/rme-2016-0065>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1514941/1/Bartlett%20complete%20formatted%20manuscript%20%28with%20figures%20at%20end%29.pdf