eprintid: 1514406 rev_number: 27 eprint_status: archive userid: 608 dir: disk0/01/51/44/06 datestamp: 2016-09-04 18:01:52 lastmod: 2021-09-20 22:37:20 status_changed: 2017-05-03 11:18:50 type: article metadata_visibility: show creators_name: Cavanagh, SE creators_name: Malalasekera, N creators_name: Kennerley, SW title: In the blink of an eye: Value and novelty drive saccades ispublished: pub divisions: UCL divisions: B02 divisions: C07 divisions: D07 divisions: F84 note: Copyright © 2015. This manuscript version is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International licence (CC BY-NC-ND 4.0). This licence allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licences are available at http://creativecommons.org/licenses/by/4.0. Access may be initially restricted by the publisher. abstract: Evidence accumulation is an essential component of value-based decisions. Recent human studies suggest that overt attention correlates with evidence accumulation necessary for optimal decisions. However, the influence of covert attention on decision-making remains relatively unexplored. To investigate this issue, two monkeys were trained to perform a decision-making task where they chose between two stimuli, which were either ‘Overtrained’ or learned that day (‘Novel’). Subjects could freely saccade during choice evaluation and indicated their decision by moving a joystick. Saccades were made within 170 ms of stimulus presentation and were strongly driven by both value and novelty, implying covert stimulus evaluation prior to saccade. This effect was strongest for ‘Overtrained’ choices, but rapidly emerged during learning of ‘Novel’ choices. Though novel stimuli attracted initial saccades, final decisions were guided only by value; implying attentional value comparison processes are at least partially dissociable from value comparison processes that govern final decisions. While subjects made highly optimal decisions, they frequently viewed only one stimulus; final choice was thus best explained by assuming covert evidence accumulation. Our results suggest that the primate brain contains multiple value comparison systems for guiding attention toward highly valuable or novel information while simultaneously optimizing final decision value. date: 2015-09 date_type: published official_url: http://dx.doi.org/10.1016/j.amsu.2015.07.013 oa_status: green full_text_type: pub pmcid: PMC4991740 language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1155121 doi: 10.1016/j.amsu.2015.07.013 lyricists_name: Cavanagh, Sean lyricists_name: Kennerley, Steven lyricists_id: SECAV40 lyricists_id: SWKEN38 full_text_status: public publication: Annals of Medicine and Surgery volume: 4 number: 3 pagerange: 319-320 issn: 2049-0801 citation: Cavanagh, SE; Malalasekera, N; Kennerley, SW; (2015) In the blink of an eye: Value and novelty drive saccades. Annals of Medicine and Surgery , 4 (3) pp. 319-320. 10.1016/j.amsu.2015.07.013 <https://doi.org/10.1016/j.amsu.2015.07.013>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/1514406/1/Kennerly_Final_1-s2.0-S2049080115000709-main.pdf