%J Proceedings of the 24th International Society for Magnetic Resonance in Medicine
%V 24
%A E Biondetti
%A DL Thomas
%A K Shmueli
%S Annual Meeting of the International Society for Magnetic Resonance in Medicine
%O Copyright © 2015 ISMRM, All Rights Reserved.
%D 2016
%T Application of Laplacian-based Methods to Multi-echo Phase Data for Accurate Susceptibility Mapping
%L discovery1508488
%I ISMRM
%B Proceedings of the 24th Annual Meeting of the International Society for Magnetic Resonance in Medicine 2016
%C Singapore
%X In Susceptibility Mapping (SM) using multi-echo gradient-echo phase data, unwrapping and/or background-Ã’eld removal is often performed using Laplacian-based methods.
However, SM pipelines in the literature have applied these methods at di×erent stages. Here, using simulated and acquired images, we compared the performance of three pipelines that apply Laplacian-based methods at di× erent stages. We showed that Laplacian-based methods alter the linearity of the phase over time. We demonstrated that only a processing pipeline that takes this into account, i.e. by Òtting the multi-echo data over time to correctly
estimate a Ã’eld map before applying Laplacian-based methods, gives accurate susceptibility values.