?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Application+of+Laplacian-based+Methods+to+Multi-echo+Phase+Data+for+Accurate+Susceptibility+Mapping&rft.creator=Biondetti%2C+E&rft.creator=Thomas%2C+DL&rft.creator=Shmueli%2C+K&rft.description=In+Susceptibility+Mapping+(SM)+using+multi-echo+gradient-echo+phase+data%2C+unwrapping+and%2For+background-%C3%92eld+removal+is+often+performed+using+Laplacian-based+methods.%0D%0AHowever%2C+SM+pipelines+in+the+literature+have+applied+these+methods+at+di%C3%97erent+stages.+Here%2C+using+simulated+and+acquired+images%2C+we+compared+the+performance+of+three+pipelines+that+apply+Laplacian-based+methods+at+di%C3%97+erent+stages.+We+showed+that+Laplacian-based+methods+alter+the+linearity+of+the+phase+over+time.+We+demonstrated+that+only+a+processing+pipeline+that+takes+this+into+account%2C+i.e.+by+%C3%92tting+the+multi-echo+data+over+time+to+correctly%0D%0Aestimate+a+%C3%92eld+map+before+applying+Laplacian-based+methods%2C+gives+accurate+susceptibility+values.&rft.publisher=ISMRM&rft.date=2016-05&rft.type=Proceedings+paper&rft.publisher=24th+Annual+Meeting+of+the+International+Society+for+Magnetic+Resonance+in+Medicine&rft.language=eng&rft.source=+++++In%3A++Proceedings+of+the+24th+Annual+Meeting+of+the+International+Society+for+Magnetic+Resonance+in+Medicine+2016.++++ISMRM%3A+Singapore.+(2016)+++++&rft.format=text&rft.identifier=https%3A%2F%2Fdiscovery.ucl.ac.uk%2Fid%2Feprint%2F1508488%2F1%2FBiondetti_Laplacian_Averaging_ISMRM2016_1547.pdf&rft.identifier=https%3A%2F%2Fdiscovery.ucl.ac.uk%2Fid%2Feprint%2F1508488%2F&rft.rights=open