eprintid: 1501088 rev_number: 37 eprint_status: archive userid: 608 dir: disk0/01/50/10/88 datestamp: 2017-03-08 12:48:53 lastmod: 2021-10-10 22:59:53 status_changed: 2017-03-08 12:48:53 type: proceedings_section metadata_visibility: show creators_name: Burgos, N creators_name: Guerreiro, F creators_name: McClelland, J creators_name: Nill, S creators_name: Dearnaley, D creators_name: Desouza, N creators_name: Oelfke, U creators_name: Knopf, AC creators_name: Ourselin, S creators_name: Cardoso, MJ title: Joint segmentation and CT synthesis for MRI-only radiotherapy treatment planning ispublished: pub divisions: UCL divisions: B04 divisions: C05 divisions: F42 note: Copyright © Springer International Publishing AG 2016. The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-319-46723-8_63 abstract: Accurate knowledge of organ location and tissue attenuation properties are the two essential components to perform radiotherapy treatment planning (RTP). Computed tomography (CT) has been the modality of choice for RTP as it easily provides electron density information. However, its low soft tissue contrast limits the accuracy of organ delineation. On the contrary, magnetic resonance (MR) provides images with excellent soft tissue contrast but its use for RTP is limited by the fact that it does not readily provide tissue attenuation information. In this work we propose a multi-atlas information propagation scheme that jointly segments the organs at risk and generates pseudo CT data from MR images. We demonstrate that the proposed framework is able to automatically generate accurate pseudo CT images and segmentations in the pelvic region, bypassing the need for CT scan for accurate RTP. date: 2016-10-02 date_type: published publisher: Springer official_url: https://doi.org/10.1007/978-3-319-46723-8_63 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1137826 doi: 10.1007/978-3-319-46723-8_63 isbn_13: 9783319467221 lyricists_name: Burgos, Ninon lyricists_name: Cardoso, Manuel lyricists_name: McClelland, James lyricists_name: Ourselin, Sebastien lyricists_id: BURGO78 lyricists_id: MJMCA47 lyricists_id: JRMCC68 lyricists_id: SOURS59 actors_name: Burgos, Ninon actors_id: BURGO78 actors_role: owner full_text_status: public series: Lecture Notes in Computer Science publication: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) volume: 9901 place_of_pub: Cham, Switzerland pagerange: 547-555 event_title: MICCAI 2016: Medical Image Computing and Computer-Assisted Intervention issn: 1611-3349 book_title: International Conference on Medical Image Computing and Computer-Assisted Intervention editors_name: Ourselin, S editors_name: Joskowicz, L editors_name: Sabuncu, M editors_name: Unal, G editors_name: Wells, W citation: Burgos, N; Guerreiro, F; McClelland, J; Nill, S; Dearnaley, D; Desouza, N; Oelfke, U; ... Cardoso, MJ; + view all <#> Burgos, N; Guerreiro, F; McClelland, J; Nill, S; Dearnaley, D; Desouza, N; Oelfke, U; Knopf, AC; Ourselin, S; Cardoso, MJ; - view fewer <#> (2016) Joint segmentation and CT synthesis for MRI-only radiotherapy treatment planning. In: Ourselin, S and Joskowicz, L and Sabuncu, M and Unal, G and Wells, W, (eds.) International Conference on Medical Image Computing and Computer-Assisted Intervention. (pp. pp. 547-555). Springer: Cham, Switzerland. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/1501088/1/miccai_2016_ninon_final_version.pdf