eprintid: 1498351
rev_number: 24
eprint_status: archive
userid: 608
dir: disk0/01/49/83/51
datestamp: 2016-06-12 01:20:07
lastmod: 2020-02-13 03:19:43
status_changed: 2016-11-11 10:14:00
type: article
metadata_visibility: show
creators_name: Wheeler, DC
creators_name: Kasiske, BL
title: Statins for hemodialysis patients with diabetes? Long-term follow-up endorses the original conclusions of the 4D Study
ispublished: pub
divisions: UCL
divisions: A01
divisions: B02
divisions: C10
divisions: D17
divisions: G93
keywords: Science & Technology, Life Sciences & Biomedicine, Urology & Nephrology, LOWERING LDL CHOLESTEROL, CHRONIC KIDNEY-DISEASE, CONTROLLED-TRIAL, METAANALYSIS, SIMVASTATIN, THERAPY
note: Copyright © 2016, International Society of Nephrology. Published by Elsevier Inc. All rights reserved. This manuscript version is made available under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International license (CC BY-NC-ND 4.0). This license allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licenses are available at http://creativecommons.org/ licenses/by/4.0. Access may be initially restricted by the publisher.
abstract: The clinical benefits of statins in dialysis patients are unproven. New follow-up data from the 4D Study indicate no clear reduction in cardiovascular events among patients with type-2 diabetes. Assessing outcomes 7.4 years beyond the randomization period (20 mg atorvastatin versus placebo), no differences in a composite cardiovascular outcome were observed and no safety concerns emerged. Current Kidney Disease: Improving Global Outcomes (KDIGO) guidelines do not need updating based on these new data.
date: 2016-06
date_type: published
publisher: NATURE PUBLISHING GROUP
official_url: http://doi.org/10.1016/j.kint.2016.02.045
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
article_type_text: Editorial Material
verified: verified_manual
elements_id: 1132413
doi: 10.1016/j.kint.2016.02.045
lyricists_name: Wheeler, David
lyricists_id: DWHEE12
full_text_status: public
publication: Kidney International
volume: 89
number: 6
pagerange: 1189-1191
pages: 3
issn: 0085-2538
citation:        Wheeler, DC;    Kasiske, BL;      (2016)    Statins for hemodialysis patients with diabetes? Long-term follow-up endorses the original conclusions of the 4D Study.                   Kidney International , 89  (6)   pp. 1189-1191.    10.1016/j.kint.2016.02.045 <https://doi.org/10.1016/j.kint.2016.02.045>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1498351/1/wheeler_Attached%20standard%20file-%20Longterm%20outcomes%20of%20the%204D%20study%20R1%20revision.pdf