eprintid: 148083 rev_number: 72 eprint_status: archive userid: 608 dir: disk0/00/14/80/83 datestamp: 2010-10-28 15:31:20 lastmod: 2021-12-13 01:52:33 status_changed: 2014-02-06 15:05:26 type: article metadata_visibility: show item_issues_count: 0 creators_name: Marlow, LAV creators_name: Waller, J creators_name: Wardle, J title: Trust and experience as predictors of HPV vaccine acceptance ispublished: pub divisions: UCL divisions: B02 divisions: D12 divisions: G19 keywords: Human Papillomavirus, trust, past experience, parents, adolescent, parental attitudes, immunization, children, future note: This is the authors' accepted version of this publication. abstract: Background: Awareness of factors associated with uptake of new childhood vaccinations could help physicians focus attention on parents who are most likely to decline to help and ensure that they are fully informed before making a vaccination decision.Aim: To examine the association between general vaccine attitudes, trust in doctors and the government, past experience with vaccination and acceptance of HPV vaccination.Design: School-based survey.Setting: Questionnaires were sent through 10 schools in England.Participants: Questionnaires were sent to 1205 mothers of 8-14 year old girls. Responses from 684 mothers were included in analyses. Outcome measures: Intended acceptance of prophylactic HPV vaccination.Results: Mothers who had high trust in doctors or the government were more likely to accept the vaccine (OR = 1.35, CI:1.22-1.50), as were those who believed their own doctor would take their vaccine concerns seriously (OR = 1.70, CI: 1.23-2.36). Mothers who had delayed (OR = 0.31, Cl: 0.19-0.51), refused (OR = 0.33, CI: 0.18-0.59) or regretted (OR = 0.43, CI: 0.19-0.99) a previous paediatric vaccination were less likely to accept the HPV vaccine. The child having experienced adverse effects from a previous vaccination was not significantly associated with acceptance (OR = 0.48, CI: 0.21-1.10).Conclusions: Past experience and trust in doctors and government were associated with differential acceptance of a new vaccine. These results suggest that doctors should listen to parents' worries about vaccination, especially parents who have previously delayed or refused vaccines. It may also be beneficial for health information to emphasize the general importance of vaccination as an effective disease prevention strategy. date: 2007-09 publisher: LANDES BIOSCIENCE official_url: http://dx.doi.org/10.4161/hv.3.5.4310 vfaculties: VFPHS oa_status: green full_text_type: other language: eng primo: open primo_central: open_green article_type_text: Article verified: verified_manual elements_source: Web of Science elements_id: 101294 doi: 10.4161/hv.3.5.4310 language_elements: EN lyricists_name: Marlow, Laura lyricists_name: Waller, Josephine lyricists_name: Wardle, Jane lyricists_id: LMARL95 lyricists_id: JWALL05 lyricists_id: FJWAR41 full_text_status: public publication: Human Vaccines volume: 3 number: 5 pagerange: 171 - 175 issn: 1554-8619 citation: Marlow, LAV; Waller, J; Wardle, J; (2007) Trust and experience as predictors of HPV vaccine acceptance. Human Vaccines , 3 (5) 171 - 175. 10.4161/hv.3.5.4310 <https://doi.org/10.4161/hv.3.5.4310>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/148083/1/Jo_Waler_Final%20manuscript%20with%20tables.pdf