eprintid: 1474732
rev_number: 24
eprint_status: archive
userid: 608
dir: disk0/01/47/47/32
datestamp: 2016-02-16 15:36:13
lastmod: 2021-11-01 02:09:17
status_changed: 2016-02-16 15:36:13
type: article
metadata_visibility: show
creators_name: Sillitoe, I
creators_name: Dawson, N
creators_name: Thornton, J
creators_name: Orengo, C
title: The history of the CATH structural classification of protein domains
ispublished: pub
divisions: UCL
divisions: B02
divisions: C08
divisions: D09
divisions: G03
keywords: Protein structure, Structure classification
note: © 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license
(http://creativecommons.org/licenses/by/4.0/).
abstract: This article presents a historical review of the protein structure classification database CATH. Together with the SCOP database, CATH remains comprehensive and reasonably up-to-date with the now more than 100,000 protein structures in the PDB. We review the expansion of the CATH and SCOP resources to capture predicted domain structures in the genome sequence data and to provide information on the likely functions of proteins mediated by their constituent domains. The establishment of comprehensive function annotation resources has also meant that domain families can be functionally annotated allowing insights into functional divergence and evolution within protein families.
date: 2015-12-01
date_type: published
official_url: http://dx.doi.org/10.1016/j.biochi.2015.08.004
oa_status: green
full_text_type: pub
pmcid: PMC4678953
language: eng
primo: open
primo_central: open_green
article_type_text: Journal Article
verified: verified_manual
elements_id: 1045413
doi: 10.1016/j.biochi.2015.08.004
pii: S0300-9084(15)00251-5
language_elements: eng
lyricists_name: Orengo, Christine
lyricists_name: Sillitoe, Ian
lyricists_name: Willhoft, Natalie
lyricists_id: CAORE63
lyricists_id: ISILL22
lyricists_id: NLDAW78
actors_name: Barczynska, Patrycja
actors_id: PBARC91
actors_role: owner
full_text_status: public
publication: Biochimie
volume: 119
pagerange: 209-217
event_location: France
issn: 1638-6183
citation:        Sillitoe, I;    Dawson, N;    Thornton, J;    Orengo, C;      (2015)    The history of the CATH structural classification of protein domains.                   Biochimie , 119    pp. 209-217.    10.1016/j.biochi.2015.08.004 <https://doi.org/10.1016/j.biochi.2015.08.004>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1474732/1/1-s2.0-S0300908415002515-main.pdf