%C Honolulu, Hawaii
%I OHBM
%L discovery1474345
%X This work validates the estimation of neurite dispersion anisotropy in the brain, using Bingham-NODDI [1], an extension of the diffusion MRI technique
called NODDI [2]. The original NODDI provides indices of neurite (axons and dendrites) morphology that are sensitive and specific to microstructural
changes [3-7]. Bingham-NODDI additionally allows the estimation of neurite dispersion anisotropy, which can enhance the accuracy of tractography
algorithms [8]. The in vivo feasibility of Bingham-NODDI has been evaluated in [1]. The present study validates its indices using high-resolution ex
vivo imaging data of the human primary visual cortex (V1), a well characterised region of the neocortex known to include fibres that fan or bend into
the cortical layers.
%T Validation of NODDI estimation of dispersion anisotropy in V1 of the human neocortex
%A M Tariq
%A M Kleinnijenhuis
%A A-M van Cappellen van Walsum
%A H Zhang
%O This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
%D 2015
%S Organization for Human Brain Mapping (OHBM)
%V 21
%B Proceedings of Organization for Human Brain Mapping (OHBM), 21st Annual Meeting