TY - GEN T3 - Organization for Human Brain Mapping (OHBM) A1 - Tariq, M A1 - Kleinnijenhuis, M A1 - van Cappellen van Walsum, A-M A1 - Zhang, H CY - Honolulu, Hawaii PB - OHBM UR - https://discovery.ucl.ac.uk/id/eprint/1474345/ ID - discovery1474345 N2 - This work validates the estimation of neurite dispersion anisotropy in the brain, using Bingham-NODDI [1], an extension of the diffusion MRI technique called NODDI [2]. The original NODDI provides indices of neurite (axons and dendrites) morphology that are sensitive and specific to microstructural changes [3-7]. Bingham-NODDI additionally allows the estimation of neurite dispersion anisotropy, which can enhance the accuracy of tractography algorithms [8]. The in vivo feasibility of Bingham-NODDI has been evaluated in [1]. The present study validates its indices using high-resolution ex vivo imaging data of the human primary visual cortex (V1), a well characterised region of the neocortex known to include fibres that fan or bend into the cortical layers. N1 - This version is the version of record. For information on re-use, please refer to the publisher?s terms and conditions. AV - public Y1 - 2015/06/14/ TI - Validation of NODDI estimation of dispersion anisotropy in V1 of the human neocortex ER -