%0 Generic
%A Tariq, M
%A Kleinnijenhuis, M
%A van Cappellen van Walsum, A-M
%A Zhang, H
%C Honolulu, Hawaii
%D 2015
%F discovery:1474345
%I OHBM
%T Validation of NODDI estimation of dispersion anisotropy in V1 of the human neocortex
%U https://discovery.ucl.ac.uk/id/eprint/1474345/
%V 21
%X This work validates the estimation of neurite dispersion anisotropy in the brain, using Bingham-NODDI [1], an extension of the diffusion MRI technique  called NODDI [2]. The original NODDI provides indices of neurite (axons and dendrites) morphology that are sensitive and specific to microstructural  changes [3-7]. Bingham-NODDI additionally allows the estimation of neurite dispersion anisotropy, which can enhance the accuracy of tractography  algorithms [8]. The in vivo feasibility of Bingham-NODDI has been evaluated in [1]. The present study validates its indices using high-resolution ex  vivo imaging data of the human primary visual cortex (V1), a well characterised region of the neocortex known to include fibres that fan or bend into  the cortical layers.
%Z This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.