@inproceedings{discovery1474345, series = {Organization for Human Brain Mapping (OHBM)}, publisher = {OHBM}, address = {Honolulu, Hawaii}, note = {This version is the version of record. For information on re-use, please refer to the publisher's terms and conditions.}, month = {June}, volume = {21}, title = {Validation of NODDI estimation of dispersion anisotropy in V1 of the human neocortex}, booktitle = {Proceedings of Organization for Human Brain Mapping (OHBM), 21st Annual Meeting}, year = {2015}, url = {https://discovery.ucl.ac.uk/id/eprint/1474345/}, abstract = {This work validates the estimation of neurite dispersion anisotropy in the brain, using Bingham-NODDI [1], an extension of the diffusion MRI technique called NODDI [2]. The original NODDI provides indices of neurite (axons and dendrites) morphology that are sensitive and specific to microstructural changes [3-7]. Bingham-NODDI additionally allows the estimation of neurite dispersion anisotropy, which can enhance the accuracy of tractography algorithms [8]. The in vivo feasibility of Bingham-NODDI has been evaluated in [1]. The present study validates its indices using high-resolution ex vivo imaging data of the human primary visual cortex (V1), a well characterised region of the neocortex known to include fibres that fan or bend into the cortical layers.}, author = {Tariq, M and Kleinnijenhuis, M and van Cappellen van Walsum, A-M and Zhang, H} }