TY  - JOUR
KW  - Propargylic alcohols
KW  -  Bronsted acid
KW  -  Nucleophilic substitution
KW  -  Friedel-Crafts reaction
KW  -  Homogeneous catalysis
ID  - discovery1473231
N2  - The activity of HBF4 (aqueous solution) as a catalyst in propargylation reactions is presented. Diverse types of nucleophiles were employed in order to form new C?O, C?N and C?C bonds in technical acetone and in air. Good to excellent yields and good chemoselectivities were obtained using low acid loading (typically 1 mol-%) under simple reaction conditions.
EP  - 7549
Y1  - 2015/12//
AV  - public
TI  - HBF4-Catalysed Nucleophilic Substitutions of Propargylic Alcohols
A1  - Barreiro, E
A1  - Sanz-Vidal, A
A1  - Tan, E
A1  - Lau, S-H
A1  - Sheppard, TD
A1  - Diez-Gonzalez, S
JF  - European Journal of Organic Chemistry
SN  - 1434-193X
UR  - http://dx.doi.org/10.1002/ejoc.201501249
N1  - © 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
IS  - 34
SP  - 7544
VL  - 2015
ER  -