TY  - JOUR
TI  - A lactate-derived chiral aldehyde for determining the enantiopurity of enantioenriched primary amines
EP  - 9054
Y1  - 2015/09/14/
AV  - public
VL  - 13
SP  - 9050
N1  - This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
IS  - 34
ID  - discovery1471701
N2  - In this paper we describe the use of a chiral aldehyde derived from lactate esters for determining the enantiopurity of primary amines, via the formation of diastereomeric imines. The method was shown to be suitable for reproducibly determining the enantiopurity of a diverse set of chiral amines. Both enantiomers of the aldehyde can be prepared in two steps from commercially available materials.
SN  - 1477-0539
UR  - http://dx.doi.org/10.1039/c5ob01398d
JF  - Organic & Biomolecular Chemistry
A1  - Gibson, SM
A1  - Lanigan, RM
A1  - Benhamou, L
A1  - Aliev, AE
A1  - Sheppard, TD
ER  -