eprintid: 1471377
rev_number: 34
eprint_status: archive
userid: 608
dir: disk0/01/47/13/77
datestamp: 2015-11-09 10:59:38
lastmod: 2021-11-07 23:53:22
status_changed: 2015-11-09 10:59:38
type: article
metadata_visibility: show
creators_name: Pallares, RM
creators_name: Kong, SL
creators_name: Hui Ru, T
creators_name: Thanh, NTK
creators_name: Lu, Y
creators_name: Su, X
title: A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification
ispublished: pub
divisions: UCL
divisions: B04
divisions: C06
divisions: F60
abstract: A plasmonic nanosensor (using gold nanorods) with inverse sensitivity is presented for circulating cell-free DNA quantification. The inverse sensitivity (i.e. the lower the analyte concentration, the higher the response intensity) is achieved by the unusual DNA concentration-dependent gold nanorod aggregation. This assay method can adjust the dynamic range by controlling the concentration of nanoparticles in solution.

Graphical abstract: A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification
date: 2015-10-04
date_type: published
official_url: http://dx.doi.org/10.1039/C5CC05331E
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1050373
doi: 10.1039/C5CC05331E
lyricists_name: Molto Pallares, Roger
lyricists_name: Nguyen, Thanh
lyricists_id: RMOLT49
lyricists_id: TTKNG00
actors_name: Molto Pallares, Roger
actors_id: RMOLT49
actors_role: owner
full_text_status: public
publication: Chemical Communications
volume: 51
number: 77
pagerange: 14524-14527
issn: 1364-548X
citation:        Pallares, RM;    Kong, SL;    Hui Ru, T;    Thanh, NTK;    Lu, Y;    Su, X;      (2015)    A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification.                   Chemical Communications , 51  (77)   pp. 14524-14527.    10.1039/C5CC05331E <https://doi.org/10.1039/C5CC05331E>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1471377/1/ChemComm-Inverse%20Sensitivity%20Sensing-Author%20version.pdf