eprintid: 1471 rev_number: 58 eprint_status: archive userid: 1 dir: disk0/00/00/14/71 datestamp: 2006-01-10 12:00:00 lastmod: 2021-12-06 00:33:44 status_changed: 2008-01-09 13:30:55 type: article metadata_visibility: show item_issues_count: 0 creators_name: McCaffery, K creators_name: Waller, J creators_name: Forrest, S creators_name: Cadman, L creators_name: Szarewski, A creators_name: Wardle, J title: Testing positive for human papillomavirus in routine cervical screening: examination of psychosocial impact ispublished: pub subjects: 3000 divisions: UCL divisions: B02 divisions: D12 divisions: G19 keywords: Young-women, Natural-history, Cancer, HPV, Infections, Trial, Population, Colposcopy, Management, Health note: This is the pre-peer reviewed version of the following article:McCaffery, K; Waller, J; Forrest, S; Cadman, L; Szarewski, A; Wardle, J; (2004) Testing positive for human papillomavirus in routine cervical screening: examination of psychosocial impact. BJOG: An International Journal of Obstetrics & Gynaecology , 111 (12) 1437 - 1443., which has been published in final form at http://dx.doi.org/10.1111/j.1471-0528.2004.00279.x. abstract: Objective To examine the psychosocial impact of testing positive for high risk human papillomavirus (HPV) among women attending primary cervical screening.Design Cross sectional survey.Measures were taken at baseline and one week after the receipt of HPV and cytology screening results.Setting Well women's clinic in London, UK.Population or Sample Four hundred and twenty-eight women aged 20-64 years.Methods Postal questionnaire survey.Main outcome measures Psychosocial and psychosexual outcomes were anxiety, distress and feelings about current, past and future sexual relationships.Results Women with normal cytology who tested positive for HPV (HPVdivided by) were significantly more anxious and distressed than women who were negative (HPV-) using both a state anxiety measure [F(1,267)=29, P<0.0001] and a screening specific measure of psychological distress [F(1,267)=69, P<0.0001]. Women with an abnormal or unsatisfactory smear result, who tested HPV,. were significantly more distressed than HPV- women with the same smear result [F(1,267)=8.8, P=0.002], but there was no significant difference in state anxiety. Irrespective of cytology result, HPV women reported feeling significantly worse about their sexual relationships. Approximately one-third of women who tested positive reported feeling worse about past and future sexual relationships compared with less than 2% of HPV- women.Conclusion The findings suggest that testing positive for HPV may have an adverse psychosocial impact, with increased anxiety., distress and concern about sexual relationships. Psychosocial outcomes of HPV testing need further investigation and must be considered alongside clinical and economic decisions to include HPV testing in routine cervical screening. date: 2004-12 date_type: published publisher: BLACKWELL PUBLISHING LTD official_url: http://dx.doi.org/10.1111/j.1471-0528.2004.00279.x vfaculties: VFPHS oa_status: green full_text_type: other language: eng primo: open primo_central: open_green article_type_text: Article verified: verified_manual elements_source: Web of Science elements_id: 59587 doi: 10.1111/j.1471-0528.2004.00279.x lyricists_name: Waller, Josephine lyricists_name: Wardle, Jane lyricists_id: JWALL05 lyricists_id: FJWAR41 full_text_status: public publication: BJOG: An International Journal of Obstetrics & Gynaecology volume: 111 number: 12 pagerange: 1437 -1443 refereed: TRUE issn: 1470-0328 citation: McCaffery, K; Waller, J; Forrest, S; Cadman, L; Szarewski, A; Wardle, J; (2004) Testing positive for human papillomavirus in routine cervical screening: examination of psychosocial impact. BJOG: An International Journal of Obstetrics & Gynaecology , 111 (12) 1437 -1443. 10.1111/j.1471-0528.2004.00279.x <https://doi.org/10.1111/j.1471-0528.2004.00279.x>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/1471/2/mccaffery_bjog_ucl_format.pdf