TY - JOUR KW - st0387 KW - smcfcs KW - multiple imputation KW - substantive model compatible KW - congenial KW - interactions KW - nonlinearities ID - discovery1470042 N2 - Multiple imputation (MI) is a practical, principled approach to handling missing data. When used to impute missing values in covariates of regression models, imputation models may be mis-specified if they are not compatible with the substantive model of interest for the outcome. In this article we introduce the smcfcs command, which imputes covariates by substantive model compatible fully conditional specification (SMC{FCS). This modifies the popular FCS or chained equations approach to MI by imputing each covariate compatibly with a user-specified substantive model. The smcfcs command is compared to standard FCS imputation using mi impute chained in a simulation study and illustrative analysis of data from a study investigating time to tumour recurrence in breast cancer. TI - Multiple imputation of covariates by substantive-model compatible fully conditional specification EP - 456 AV - public Y1 - 2015/06// JF - The Stata Journal A1 - Bartlett, JW A1 - Morris, TP SN - 1536-867X UR - http://www.stata-journal.com/article.html?article=st0387 N1 - © Copyright 2001?2015 StataCorp LP IS - 2 SP - 437 VL - 15 ER -