eprintid: 1470018
rev_number: 25
eprint_status: archive
userid: 608
dir: disk0/01/47/00/18
datestamp: 2015-10-08 12:51:40
lastmod: 2021-09-26 22:48:02
status_changed: 2015-10-08 12:51:40
type: article
metadata_visibility: show
creators_name: Luo, L
creators_name: Lane, ME
title: Topical and transdermal delivery of caffeine.
ispublished: pub
divisions: UCL
divisions: B02
divisions: C08
divisions: D10
divisions: G08
keywords: Caffeine, Formulation, Permeation, Topical, Transdermal
note: Pre-print version
abstract: Caffeine is administered topically and transdermally for a variety of pharmaceutical and cosmetic applications and it is also used as a model hydrophilic compound in dermal risk assessment studies. This review considers the physicochemical and permeation properties of caffeine with reference to its delivery to and through the skin. Since it has been used as a model compound the findings have implications for the delivery of many hydrophilic compounds having similar properties. Various passive and active formulation strategies to promote enhanced skin permeation of caffeine are considered. Models to study percutaneous caffeine penetration are also discussed in detail.
date: 2015-05-21
date_type: published
official_url: http://dx.doi.org/10.1016/j.ijpharm.2015.05.050
vfaculties: VFLS
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
article_type: review
article_type_text: Journal Article
verified: verified_manual
elements_id: 1036040
doi: 10.1016/j.ijpharm.2015.05.050
pii: S0378-5173(15)00469-X
language_elements: eng
lyricists_name: Lane, Majella
lyricists_name: Luo, Lin
lyricists_id: MLANE69
lyricists_id: LLUOX97
actors_name: Lane, Majella
actors_id: MLANE69
actors_role: owner
full_text_status: public
publication: International Journal of Pharmaceutics
volume: 490
number: 1-2
pagerange: 155-164
event_location: Netherlands
issn: 1873-3476
citation:        Luo, L;    Lane, ME;      (2015)    Topical and transdermal delivery of caffeine.           [Review].        International Journal of Pharmaceutics , 490  (1-2)   pp. 155-164.    10.1016/j.ijpharm.2015.05.050 <https://doi.org/10.1016/j.ijpharm.2015.05.050>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1470018/1/IJP-D-15-00361R3%20%284%29.pdf