eprintid: 1468929
rev_number: 27
eprint_status: archive
userid: 608
dir: disk0/01/46/89/29
datestamp: 2015-05-28 13:18:31
lastmod: 2020-02-12 15:01:10
status_changed: 2015-05-28 13:18:31
type: article
metadata_visibility: show
item_issues_count: 0
creators_name: Rose, AM
creators_name: Hall, CS
creators_name: Martinez-Alier, N
title: Aetiology and management of malnutrition in HIV-positive children
ispublished: pub
divisions: UCL
divisions: A01
divisions: B02
divisions: C07
note: This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/
abstract: Worldwide, more than 3 million children are infected with HIV and, without treatment, mortality among these children is extremely high. Both acute and chronic malnutrition are major problems for HIV-positive children living in resource-limited settings. Malnutrition on a background of HIV represents a separate clinical entity, with unique medical and social aetiological factors. Children with HIV have a higher daily calorie requirement than HIV-negative peers and also a higher requirement for micronutrients; furthermore, coinfection and chronic diarrhoea due to HIV enteropathy play a major role in HIV-associated malnutrition. Contributory factors include late presentation to medical services, unavailability of antiretroviral therapy, other issues surrounding healthcare provision and food insecurity in HIV-positive households. Treatment protocols for malnutrition have been greatly improved, yet there remains a discrepancy in mortality between HIV-positive and HIV-negative children. In this review, the aetiology, prevention and treatment of malnutrition in HIV-positive children are examined, with particular focus on resource-limited settings where this problem is most prevalent. © 2014 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
date: 2014-01-09
official_url: http://dx.doi.org/10.1136/archdischild-2012-303348
vfaculties: VFBRS
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_source: Scopus
elements_id: 927174
doi: 10.1136/archdischild-2012-303348
lyricists_name: Rose, Anna
lyricists_id: AMROS57
full_text_status: public
publication: Archives of Disease in Childhood
volume: 99
number: 6
pagerange: 546- 551
issn: 0003-9888
citation:        Rose, AM;    Hall, CS;    Martinez-Alier, N;      (2014)    Aetiology and management of malnutrition in HIV-positive children.                   Archives of Disease in Childhood , 99  (6)   546- 551.    10.1136/archdischild-2012-303348 <https://doi.org/10.1136/archdischild-2012-303348>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1468929/1/Arch%20Dis%20Child-2014-Rose-546-51.pdf