eprintid: 1467106
rev_number: 30
eprint_status: archive
userid: 608
dir: disk0/01/46/71/06
datestamp: 2015-04-22 21:25:03
lastmod: 2021-09-26 22:44:47
status_changed: 2015-04-22 21:25:03
type: article
metadata_visibility: show
item_issues_count: 0
creators_name: Halpern, AR
creators_name: Golden, HL
creators_name: Magdalinou, N
creators_name: Witoonpanich, P
creators_name: Warren, JD
title: Musical tasks targeting preserved and impaired functions in two dementias.
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D07
divisions: F86
keywords: Alzheimer's disease, Parkinson's disease, auditory imagery, executive function, Aged, Alzheimer Disease, Auditory Perception, Behavior, Cognition, Dementia, Executive Function, Female, Humans, Learning, Male, Middle Aged, Music, Neuropsychological Tests, Parkinson Disease, Perception
note: © 2014 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals Inc. on behalf of The New York Academy of Sciences.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
abstract: Studies of musical abilities in dementia have for the most part been rather general assessments of abilities, for instance, assessing retention of music learned premorbidly. Here, we studied patients with dementias with contrasting cognitive profiles to explore specific aspects of music cognition under challenge. Patients suffered from Alzheimer's disease (AD), in which a primary impairment is in forming new declarative memories, or Lewy body disease (PD/LBD), a type of parkinsonism in which executive impairments are prominent. In the AD patients, we examined musical imagery. Behavioral and neural evidence confirms involvement of perceptual networks in imagery, and these are relatively spared in early stages of the illness. Thus, we expected patients to have relatively intact imagery in a mental pitch comparison task. For the LBD patients, we tested whether executive dysfunction would extend to music. We probed inhibitory skills by asking for a speeded pitch or timbre judgment when the irrelevant dimension was held constant or also changed. Preliminary results show that AD patients score similarly to controls in the imagery tasks, but PD/LBD patients are impaired relative to controls in suppressing some irrelevant musical dimensions, particularly when the required judgment varies from trial to trial.
date: 2015-03
official_url: http://dx.doi.org/10.1111/nyas.12616
vfaculties: VFBRS
oa_status: green
full_text_type: pub
primo: open
primo_central: open_green
article_type_text: Journal Article
verified: verified_manual
elements_source: PubMed
elements_id: 1021239
doi: 10.1111/nyas.12616
lyricists_name: Golden, Hannah
lyricists_name: Warren, Jason
lyricists_id: HLGOL19
lyricists_id: JDWAR75
full_text_status: public
publication: Ann N Y Acad Sci
volume: 1337
pagerange: 241-248
event_location: United States
issn: 1749-6632
citation:        Halpern, AR;    Golden, HL;    Magdalinou, N;    Witoonpanich, P;    Warren, JD;      (2015)    Musical tasks targeting preserved and impaired functions in two dementias.                   Ann N Y Acad Sci , 1337    pp. 241-248.    10.1111/nyas.12616 <https://doi.org/10.1111/nyas.12616>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1467106/1/nyas12616.pdf