eprintid: 1466816
rev_number: 33
eprint_status: archive
userid: 608
dir: disk0/01/46/68/16
datestamp: 2015-04-21 19:27:32
lastmod: 2022-01-16 00:58:08
status_changed: 2015-04-21 19:27:32
type: article
metadata_visibility: show
item_issues_count: 0
creators_name: Scharnowski, F
creators_name: Veit, R
creators_name: Zopf, R
creators_name: Studer, P
creators_name: Bock, S
creators_name: Diedrichsen, J
creators_name: Goebel, R
creators_name: Mathiak, K
creators_name: Birbaumer, N
creators_name: Weiskopf, N
title: Manipulating motor performance and memory through real-time fMRI neurofeedback
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D07
divisions: F83
keywords: Brain imaging, Brain training, Functional magnetic resonance imaging (fMRI), Memory, Motor performance, Neurofeedback, Real-time fMRI, Self-regulation
note: © 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license(http://creativecommons.org/licenses/by/4.0/).
abstract: Task performance depends on ongoing brain activity which can be influenced by attention, arousal, or motivation. However, such modulating factors of cognitive efficiency are unspecific, can be difficult to control, and are not suitable to facilitate neural processing in a regionally specific manner. Here, we non-pharmacologically manipulated regionally specific brain activity using technically sophisticated real-time fMRI neurofeedback. This was accomplished by training participants to simultaneously control ongoing brain activity in circumscribed motor and memory-related brain areas, namely the supplementary motor area and the parahippocampal cortex. We found that learned voluntary control over these functionally distinct brain areas caused functionally specific behavioral effects, i.e. shortening of motor reaction times and specific interference with memory encoding. The neurofeedback approach goes beyond improving cognitive efficiency by unspecific psychological factors such as attention, arousal, or motivation. It allows for directly manipulating sustained activity of task-relevant brain regions in order to yield specific behavioral or cognitive effects.
date: 2015-05
official_url: http://dx.doi.org/10.1016/j.biopsycho.2015.03.009
vfaculties: VFBRS
oa_status: green
full_text_type: pub
primo: open
primo_central: open_green
article_type_text: Journal Article
verified: verified_manual
elements_source: PubMed
elements_id: 1021110
doi: 10.1016/j.biopsycho.2015.03.009
pii: S0301-0511(15)00067-8
language_elements: ENG
lyricists_name: Diedrichsen, Joern
lyricists_name: Weiskopf, Nikolaus
lyricists_id: JDIED89
lyricists_id: NWEIS04
full_text_status: public
publication: Biological Psychology
volume: 108
pagerange: 85-97
event_location: Netherlands
issn: 1873-6246
citation:        Scharnowski, F;    Veit, R;    Zopf, R;    Studer, P;    Bock, S;    Diedrichsen, J;    Goebel, R;             ... Weiskopf, N; + view all <#>        Scharnowski, F;  Veit, R;  Zopf, R;  Studer, P;  Bock, S;  Diedrichsen, J;  Goebel, R;  Mathiak, K;  Birbaumer, N;  Weiskopf, N;   - view fewer <#>    (2015)    Manipulating motor performance and memory through real-time fMRI neurofeedback.                   Biological Psychology , 108    pp. 85-97.    10.1016/j.biopsycho.2015.03.009 <https://doi.org/10.1016/j.biopsycho.2015.03.009>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/1466816/1/Manipulating%20motor%20performance%20and%20memory%20through%20real-time%20fMRI%20neurofeedback.pdf
document_url: https://discovery.ucl.ac.uk/id/eprint/1466816/2/Supplementary%20data.doc